MULTI-CONTAINER FLUID TRANSFER AND DELIVERY DEVICE

• US 20130046270A1
• Filed: 04/29/2011
• Published: 02/21/2013
• Est. Priority Date: 04/29/2010
• Status: Active Grant

• Current Assignee: Yukon Medical, LLC
• Original Assignee: Yukon Medical, LLC
• Inventors: Foshee, David L., Mosler, Theodore J., Snell, Nathan R., Penny, Matthew R., Korogi, Todd M.
• Granted Patent: US 9,636,277 B2
• Time in Patent Office: Days
• US Class Current: 604/407
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2017 having three or more piercing ends
• CPC Class Codes: A61J 1/2037 having valve means
• CPC Class Codes: A61J 1/2058 having multiple connecting ports
• CPC Class Codes: A61J 1/2075 for external venting
• CPC Class Codes: A61J 1/2082 for gas filtration
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 5/1782 Devices aiding filling of syringes in situ combination of a vial and a syringe for transferring or mixing their contents A61J1/2096, filling of medical containers in general B65B3/003
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence

Abstract

A multi-container transfer and deliver device and methods of mixing and transferring, the device configured to allow multiple containers to transfer and mix their respective materials and for receiving of the mixed materials to a fluid delivery device. The transfer device comprises a plurality of flow conduits for fluid flow between the multiple containers and the fluid delivery device. A drug mixing kit and optional packaging comprising a multi-container housing with a plurality of flow conduits and a plurality of sections for receiving containers and a fluid transfer device is described.

Claims

1. A transfer device comprising:

a base plate;

an upper housing; and

a lower housing securable to the base plate , the lower housing slidably receiving a portion of the upper housing;

wherein the lower housing provides multiple compartments configured for receiving at least two containers, each having a pierceable portion associated therewith, and one of the multiple compartments configured to receive a horizontally presented delivery device; and

a fluidic conduit system integral with the lower housing providing fluid communication between at least two of the multiple compartments.

2. The device of claim 1, wherein the fluidic conduit system comprises:

(i) a vent and optionally, a check valve;

(ii) a first container accessing member having a longitudinal axis distally projecting essentially vertical from the lower housing, and having corresponding therewith a first fluid lumen and a second fluid lumen essentially parallel with the longitudinal axis, the first fluid lumen of the first container accessing member in fluid communication with the vent;

(iii) a second container accessing member having a longitudinal axis distally projecting essentially vertical from the lower housing, and having corresponding therewith a first fluid lumen and a second fluid lumen essentially parallel with the longitudinal axis, the first fluid lumen of the second container accessing member in fluid communication with the second fluid lumen of the first container accessing member; and

(iv) a delivery device accessing member having a longitudinal axis distally projecting essentially vertical from the lower housing, and having corresponding therewith a first fluid lumen essentially parallel with the longitudinal axis, the first fluid lumen of the delivery device accessing member in fluid communication with the second fluid lumen of the second container accessing member.

3. The device of claim 1, wherein the delivery device accessing member further comprises a fluid flow controller.

4. The device of claim 3, wherein the fluid flow controller comprises a collapsible elastomeric sleeve having a first state fluidically sealing the first fluid lumen of the delivery device access member, and a second state providing fluid communication between a delivery device and the fluidic conduit system.

5. The device of claim 1, wherein the lower housing comprises:

(i) a first flow channel fluidically communicating the first fluid lumen of the first container accessing member with the vent;

(ii) a second flow channel fluidically communicating the first fluid lumen of the second container accessing member with the second fluid lumen of the first container accessing member, and

(iii) a third flow channel fluidically communicating the first fluid lumen of the delivery device accessing member with the second fluid lumen of the second container accessing member;

wherein the flow channels (i)-(iii) are physically isolated from each other and form at least a portion of the fluidic conduit system by combination of the base plate and the lower housing.

9. The device of claim 1, further comprising a syringe operably positioned with the delivery device accessing member, the syringe comprising:

an adapter, the adapter comprising;

a first end for receiving the syringe, the first end having a first conduit;

a second end for receiving a dispensing member of the syringe, the second end having a second conduit; and

an adapter housing positioned between the first end and the second end and in fluidic communication therewith, the adapter housing having an opening sealed with a elastomeric septum, wherein the elastomeric septum in a first state provides fluidic communication between the first conduit and the second conduit, and in a second state, upon coupling with the delivery device accessing member, prevents fluidic communication the between the first conduit and the second conduit.

25. The device of claim 9, further comprising a one-way flow control valve.

36. A method of mixing and transferring, the method comprising:

providing a device as defined in claim 1; and

optionally, providing at least one container having a pierceable opening.

37. The method of claim 36, further comprising:

introducing at least two containers to the device such that the pierceable openings are operably configured with the first or the second container accessing member; and

sequentially or concurrently, operably coupling a syringe to the delivery device accessing member.

38. The method of claim 36, further comprising urging the upper housing towards the lower housing so that the at least two containers are accessed by the first or the second container accessing member through the pierceable openings.

39. The method of claim 36, further comprising, sequentially or concurrently, mixing and transferring at least a portion of the contents from the at least two containers into the syringe.

6. (canceled)

7. (canceled)

8. (canceled)

10. (canceled)

11. A transfer device comprising:

a base plate;

an upper housing; and

a lower housing securable to the base plate and providing multiple compartments, the lower housing slidably receiving a portion of the upper housing;

a fluidic conduit system integral with the lower housing providing fluid communication between the multiple compartments, the fluidic conduit system comprising;

(i) a first container accessing member having a longitudinal axis distally projecting essentially vertical from the lower housing, and having corresponding therewith a first fluid lumen and a second fluid lumen essentially parallel with the longitudinal axis, the first fluid lumen of the first container accessing member in fluid communication with the vent;

(ii) a second container accessing member having a longitudinal axis distally projecting essentially vertical from the lower housing, and having corresponding therewith a first fluid lumen and a second fluid lumen essentially parallel with the longitudinal axis, the first fluid lumen of the second container accessing member in fluid communication with the second fluid lumen of the first container accessing member; and

(iii) a delivery device accessing member configured to control fluid communication between a delivery device and the fluidic conduit system, the delivery device accessing member having a first fluid lumen in fluid communication with the second fluid lumen of the second container accessing member, wherein the delivery device accessing member is configured with at least one of the following;

(a) a valved access connector; and

(b) a cannula in combination with a collapsible elastomeric sleeve.

13. The transfer device of claim 11, wherein the lower housing comprises:

(i) a first flow channel fluidically communicating the first fluid lumen of the first container accessing member with a vent and/or optional check valve;

(ii) a second flow channel fluidically communicating the first fluid lumen of the second container accessing member with the second fluid lumen of the first container accessing member, and

(iii) a third flow channel fluidically communicating the first fluid lumen of the delivery device accessing member with the second fluid lumen of the second container accessing member;

the flow channels (i)-(iii) being physically isolated from each other and forming at least a portion of the fluidic conduit system by combination of the base plate and the lower housing.

14. The transfer device of any one of claim 13, further comprising a check valve in fluid communication with the first flow channel.

15. The transfer device of claim 11, wherein the valved access connector is a female valved connector or a collapsible elastomeric sleeve having a first state fluidically sealing the first fluid lumen of the delivery device access member, and a second state providing fluid communication between a delivery device and the fluidic conduit system.

16. The transfer device of claim 11, wherein the pierceable septum is configured for receiving a cannula.

20. The device of claim 11, further comprising a syringe configured to operably couple with the delivery device accessing member.

21. The device of claim 20, wherein the syringe comprises a distal end having a male valved connector having a first state fluidically sealing the distal end of the syringe, and a second state operably coupled to the delivery device accessing member so as to provide fluid communication between the syringe and the fluidic conduit system.

24. The device of claim 20, wherein the syringe comprises a distal end having a male valved connector having a first state fluidically sealing the distal end of the syringe, and a second state operably coupled to the delivery device accessing member comprising a female valved connector.

12. (canceled)

17. (canceled)

18. (canceled)

19. (canceled)

22. (canceled)

23. (canceled)

26-35. -35. (canceled)