SYSTEM AND METHOD OF INCREASING SAMPLE THROUGHPUT
First Claim
1. A system for increasing sample throughput, comprising:
- a sensor configured to generate data signals in response to being exposed to an analyte within a sample; and
a processor configured torecord data points associated with the data signals,select a series of data points corresponding to a portion of a kinetic region time range from the recorded data points,convert the selected data points to a logarithmic function of time scale,evaluate the converted data points,determine a curve that fits the evaluate data points,determine a curve fitting equation corresponding to the curve,extrapolate an end point response of the sensor using the curve fitting equation, andcalculate, using the extrapolated end point response, a value corresponding to the analyte.
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Abstract
Technologies for increasing sample throughput by predicting the end point response time of a sensor for the analysis of an analyte in a sample are disclosed. In one aspect, a system includes a sensor that generates data signals associated with the measurement of an analyte within the sample. A processor records appropriate data points corresponding to the signals, converts them to a logarithmic function of time scale, and plots the converted data points. The processor then determines a curve that fits the plotted data points and determines a curve fitting equation for the curve. Once the equation is determined, the processor extrapolates an end point response of the sensor using the equation. A value, such as analyte concentration, is then calculated using the extrapolated end point response.
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Citations
24 Claims
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1. A system for increasing sample throughput, comprising:
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a sensor configured to generate data signals in response to being exposed to an analyte within a sample; and a processor configured to record data points associated with the data signals, select a series of data points corresponding to a portion of a kinetic region time range from the recorded data points, convert the selected data points to a logarithmic function of time scale, evaluate the converted data points, determine a curve that fits the evaluate data points, determine a curve fitting equation corresponding to the curve, extrapolate an end point response of the sensor using the curve fitting equation, and calculate, using the extrapolated end point response, a value corresponding to the analyte. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method for increasing sample throughput, comprising:
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receiving, from a sensor, data signals generated in response to being exposed to an analyte within a sample; recording data points associated with the data signals; selecting a series of data points corresponding to a portion of a kinetic region time range from the recorded data points; converting the selected data points to a logarithmic function of time scale; plotting the converted data points; determining a curve that fits the plotted data points; determining a curve fitting equation corresponding to the curve; extrapolating an end point response of the sensor using the curve fitting equation; and calculating, using the extrapolated end point response, a value corresponding to the analyte. - View Dependent Claims (15, 16, 17, 18, 19, 20)
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21. A computer-readable storage medium having computer executable instructions stored thereon, which when executed by a computer, cause the computer to:
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receive, from a sensor, data signals generated in response to being exposed to an analyte within a sample; evaluate a curve defined by a second order quadratic equation that matches the data signals received from the sensor; extrapolate an end point response of the sensor using the curve; and calculate, using the extrapolated end point response, a value corresponding to the analyte. - View Dependent Claims (22, 23, 24)
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Specification