PROCESSES AND INTERMEDIATES FOR MAKING A JAK INHIBITOR
First Claim
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1. A process, comprising reacting a compound of Formula III:
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Abstract
This invention relates to processes and intermediates for making {1-{1-[3-fluoro-2-(trifluoromethyl)isonicotinoyl]piperidin-4-yl}-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile, useful in the treatment of diseases related to the activity of Janus kinases (JAK) including inflammatory disorders, autoimmune disorders, cancer, and other diseases.
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Citations
23 Claims
- 1. A process, comprising reacting a compound of Formula III:
- 17. A process of making a compound of Formula IV:
- 21. A process of making a compound of Formula V:
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23. A compound of Formula V:
Specification