DEVICE FOR REGULATING AT LEAST ONE FILTRATION VALUE, HAEMODIALYSIS MACHINE AND CORRESPONDING METHOD AND USE

• US 20130062283A1
• Filed: 03/17/2011
• Published: 03/14/2013
• Est. Priority Date: 03/19/2010
• Status: Active Grant

• Current Assignee: Fresenius Medical Care Deutschland GmbH (Fresenius Medical Care AG)
• Original Assignee: Fresenius Medical Care Deutschland GmbH (Fresenius Medical Care AG)
• Inventors: Peters, Arne, Heide, Alexander, Wiktor, Christoph
• Granted Patent: US 10,201,646 B2
• Time in Patent Office: Days
• US Class Current: 210/646
• CPC Class Codes: A61M 1/14 Dialysis systems; Artificial kidneys; Blood oxygenators semi-permeable membranes characterised by the material, manufacturing processes therefor B01D71/00 ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/1601 Control or regulation
• CPC Class Codes: A61M 1/34 Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
• CPC Class Codes: A61M 1/3403 Regulation parameters
• CPC Class Codes: A61M 1/36 Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
• CPC Class Codes: A61M 1/3607 Regulation parameters
• CPC Class Codes: A61M 1/36225 with blood pumping means or components thereof
• CPC Class Codes: A61M 1/3693 using separation based on different densities of components, e.g. centrifuging
• CPC Class Codes: A61M 1/38 Removing constituents from donor blood and storing or returning remainder to body , e.g. for transfusion
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/3379 Masses, volumes, levels of fluids in reservoirs, flow rates
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/232 Centrifugal pumps
• CPC Class Codes: A61M 60/37 Haemodialysis, haemofiltration or diafiltration
• CPC Class Codes: A61M 60/847 arranged in a cassette
• CPC Class Codes: A61M 60/849 Disposable parts
• CPC Class Codes: Y10T 137/8158 With indicator, register, recorder, alarm or inspection means

Abstract

The present invention relates to an apparatus for the regulation of at least one filtration value in a machine for the treatment of a medical fluid, in particular in a blood treatment machine, having at least one centrifugal pumping means, to a hemodialysis machine and to a method and to a use therefor.

Claims

1. An apparatus for the regulation of at least one filtration value in a machine for the treatment of a medical fluid, in particular in a blood treatment machine, having at least one centrifugal pump means,

characterized in that

the viscosity of the medical fluid can be determined indirectly and/or directly by means of the centrifugal pumping means, and with the at least one filtration value being able to be regulated with reference to the viscosity determined.

2. An apparatus in accordance with claim 1, characterized in that the centrifugal pumping means is part of a centrifugal pump or is or comprises a centrifugal pump;

and/or in that the medical fluid can be conveyed by means of the centrifugal pumping means.

3. An apparatus in accordance with claim 1, characterized in that the centrifugal pumping means can be operated in at least one conveying mode and/or at least one measurement mode.

4. An apparatus in accordance with claim 1, characterized in that the centrifugal pumping means has at least one driving first part and one driven second part.

5. An apparatus in accordance with claim 4, characterized in that a torque transmission and/or force transmission takes place from the driving first part to the driven second part by means of a magnetic coupling.

6. An apparatus in accordance with claim 1, characterized in that the viscosity of the medical fluid can be determined indirectly and/or directly with reference to the speed and driving torque of the centrifugal pumping means.

7. An apparatus in accordance with claim 1, characterized in that the apparatus is made at least partly as a disposable or has replaceable components which are made as disposables.

8. An apparatus in accordance with claim 7, characterized in that at least the driven second part of the centrifugal pumping means is arranged in the disposable;

and/or in that the disposable is made in a cassette-like manner or as a disposable cassette.

9. An apparatus in accordance with claim 1, characterized in that the machine for the treatment of a medical fluid is a hemodialysis machine;

and/or in that the filtration value or the filtration values is or are the ultrafiltration rate and/or the ultrafiltration goal.

10. An apparatus in accordance with claim 1, characterized in that the medical fluid is blood;

and in that the hematocrit value of the blood can be determined with reference to the determined viscosity.

11. An apparatus in accordance with claim 1, characterized in that the medical fluid is dialysate;

and in that the state of the blood can preferably be determined with reference to the determined viscosity.

12. An apparatus in accordance with claim 1, characterized in that the medical fluid is filtrate, for example in the plasma separation, with the viscosity of the plasma filtered there being able to be determined in a particularly advantageous manner.

13. An apparatus in accordance with claim 1, characterized in that the apparatus has at least one control and/or regulation means and/or has at least one connection which can be connected to at least one control and/or regulation means, with the viscosity of the medical fluid being able to be determined and/or the at least one filtration value being able to be regulated indirectly and/or directly by means of the control and/or regulation means.

14. An apparatus in accordance with claim 13, characterized in that the centrifugal pumping means can be switched over between the conveying mode and the measurement mode by means of the control and/or regulation means;

and/or in that the speed of the centrifugal pumping means can be regulated by means of the control and/or regulation means.

15. An apparatus in accordance with claim 1, characterized in that the centrifugal pumping means has at least one closure means at the inlet side and/or outlet side by means of which the centrifugal pumping means can be closed at the inlet side and/or at the outlet side.

16. An apparatus in accordance with claim 15, characterized in that the centrifugal pumping means can be operated in the measurement mode when at least one closure means closes the centrifugal pumping means at the inlet side and/or at the outlet side, preferably when both closure means close the centrifugal pumping means at the inlet side and at the outlet side.

17. An apparatus in accordance with claim 1, characterized in that at least one detection means, in particular a flow measurement sensor, is arranged downstream or upstream of the centrifugal pumping means for the indirect and/or direct detection and/or determination of the volume flow of the medical fluid.

18. An apparatus in accordance with claim 1, characterized in that the centrifugal pumping means can be operated in a mode with a sufficiently slow speed so that the medical fluid cannot be conveyed by the centrifugal pumping means, but can be circulated in the centrifugal pumping means or is not conveyed by the centrifugal pumping means but is circulated in it, with the sufficiently low speed preferably amounting to a few hundred revolutions per minute, in particular 200 r.p.m. or also lower, and with further preferably the viscosity of the medical fluid being able to be determined without additional flow measurement sensors and/or blocking apparatus.

19. A hemodialysis machine comprising at least one apparatus in accordance with claim 1.

20. A hemodialysis machine in accordance with claim 19, characterized in that the hemodialysis machine has a mount into which a disposable can be inserted that has at least elements of the centrifugal pumping means by means of which the viscosity of the medical fluid can be determined indirectly or directly, with the driving first part of the centrifugal pumping means preferably being arranged in the hemodialysis machine.

21. A disposable for an apparatus in accordance with claim 1, wherein the disposable has at least elements of the centrifugal pumping means by means of which the viscosity of the medical fluid can be determined indirectly and/or directly, wherein the disposable is at least a art of said apparatus made as a disposable or has replaceable components which are made as disposables.

22. A centrifugal pumping means for an apparatus in accordance with claim 1, wherein the centrifugal pumping means

is characterized in that

the viscosity of the medical fluid can be determined indirectly and/or directly by means of the centrifugal pumping means, and with the at least one filtration value being able to be regulated with reference to the viscosity determined.

23. Use of an apparatus in accordance with claim 1 for a hemodialysis machine.

24. Use of a centrifugal pumping means in a disposable for an apparatus in accordance with claim 1, wherein the disposable has at least elements of the centrifugal pumping means by means of which the viscosity of the medical fluid can be determined indirectly and/or directly.

27. A method for the regulation of at least one filtration value in a machine for the treatment of a medical fluid, in particular in a blood treatment machine, having at least one centrifugal pump means,

characterized in that

the viscosity of the medical fluid is determined indirectly and/or directly by means of the centrifugal pumping means, and with the at least one filtration value being regulated with reference to the viscosity determined, wherein the method is carried out by means of an apparatus in accordance with claim 1.

25. A method for the regulation of at least one filtration value in a machine for the treatment of a medical fluid, in particular in a blood treatment machine, having at least one centrifugal pump means,

characterized in that

the viscosity of the medical fluid is determined indirectly and/or directly by means of the centrifugal pumping means, and with the at least one filtration value being regulated with reference to the viscosity determined.

26. A method in accordance with claim 25, characterized in that the centrifugal pumping means is operated in at least one conveying mode and/or at least one measurement mode;

and/or in that the viscosity of the medical fluid is determined indirectly or directly with reference to the speed and driving torque of the centrifugal pumping means.