INTRAVASCULAR GLUCOSE SENSOR
First Claim
1. A glucose sensor for intravascular measurement of glucose concentration wherein the sensor is arranged to measure glucose concentration by monitoring the lifetime of the fluorophore, the sensor comprising:
- an indicator system comprising a receptor for selectively binding to glucose and a fluorophore associated with said receptor, wherein the fluorophore has a lifetime of less than 100 ns;
a light source;
an optical fibre arranged to direct light from the light source onto the indicator system;
a detector arranged to receive fluorescent light emitted from the indicator system; and
a signal processor arranged to determine information related to a fluorescence lifetime of the fluorophore based on at least the output signal of the detector.
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Accused Products
Abstract
A glucose sensor for intravascular measurement of glucose concentration wherein the sensor is arranged to measure glucose concentration by monitoring the lifetime of the fluorophore, the sensor comprising:—an indicator system comprising a receptor for selectively binding to glucose and a fluorophore associated with said receptor, wherein the fluorophore has a life-time of less than 100 ns;—a light source;—an optical fibre arranged to direct light from the light source onto the indicator system; —a detector arranged to receive fluorescent light emitted from the indicator system; and—a signal processor arranged to determine information related to a fluorescence lifetime of the fluorophore based on at least the output signal of the detector.
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Citations
14 Claims
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1. A glucose sensor for intravascular measurement of glucose concentration wherein the sensor is arranged to measure glucose concentration by monitoring the lifetime of the fluorophore, the sensor comprising:
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an indicator system comprising a receptor for selectively binding to glucose and a fluorophore associated with said receptor, wherein the fluorophore has a lifetime of less than 100 ns; a light source; an optical fibre arranged to direct light from the light source onto the indicator system; a detector arranged to receive fluorescent light emitted from the indicator system; and a signal processor arranged to determine information related to a fluorescence lifetime of the fluorophore based on at least the output signal of the detector. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification