FLUIDIC MANIFOLD

• US 20130081697A1
• Filed: 09/30/2011
• Published: 04/04/2013
• Est. Priority Date: 09/30/2011
• Status: Abandoned Application

• Current Assignee: DePuy Mitek Incorporated (Johnson & Johnson)
• Original Assignee: DePuy Mitek Incorporated (Johnson & Johnson)
• Inventors: Barry, Donald
• Application Number:
  US13/249,470
• Publication Number:
  US 20130081697A1
• Time in Patent Office: Days
• US Class Current: 137/1
• CPC Class Codes: A61M 2039/2473 Valve comprising a non-deformable, movable element, e.g. ball-valve, valve with movable stopper or reciprocating element
• CPC Class Codes: B01L 2200/027 for microfluidic devices
• CPC Class Codes: B01L 2300/0816 Cards, e.g. flat sample carriers usually with flow in two horizontal directions
• CPC Class Codes: B01L 2300/0861 Configuration of multiple channels and/or chambers in a single devices
• CPC Class Codes: B01L 2300/0887 Laminated structure
• CPC Class Codes: B01L 2300/123 Flexible; Elastomeric
• CPC Class Codes: B01L 2400/0481 squeezing of channels or chambers
• CPC Class Codes: B01L 2400/0605 check valves
• CPC Class Codes: B01L 2400/0655 pinch valves
• CPC Class Codes: B01L 2400/082 Active control of flow resistance, e.g. flow controllers
• CPC Class Codes: B01L 3/502707 characterised by the manufacture of the container or its components by shaping or joining plastic parts B29C59/00, B29C65/00; by laminating B32B37/00; manufacture of microstructural devices in general B81C
• CPC Class Codes: B01L 3/50273 characterised by the means or forces applied to move the fluids micropumps F04B19/006, of the membrane type F04B43/043
• CPC Class Codes: B01L 3/502738 characterised by integrated valves microvalves F16K99/0001
• CPC Class Codes: B01L 3/502746 characterised by the means for controlling flow resistance, e.g. flow controllers, baffles B01L3/502738 takes precedence
• CPC Class Codes: F04B 43/14 having plate-like flexible members
• CPC Class Codes: F16K 99/0057 the fluid being the circulating fluid itself, e.g. check valves
• CPC Class Codes: Y10T 137/0318 Processes
• CPC Class Codes: Y10T 137/85938 Non-valved flow dividers

Abstract

A fluid management cassette system comprises a first and second opposed platen with first and second opposed films compressed between the platens. One or more channels formed one or both of the platens form pathways with the films through which fluids can be directed. Valves and other flow control mechanisms can be incorporated.

Claims

1. A fluid management cassette system comprising;

a first platen and a second platen opposed to the first platen;

a first film and a second film in opposed relation to each other and compressed between the first platen and the second platen; and

one or more channels formed in at least one of the first platen and second platen whereby fluid can be directed through a pathway formed between the first film and second film at the one or more channels.

2. The fluid management cassette system of claim 1 wherein the first film has an inward face facing the second film and the second film has an inward face facing the first film and wherein the first film inward face and the second film inward face are sterile.

3. The fluid management cassette system of claim 1 and further comprising a valve comprising a valve element movable into the channel against one of the first or second films.

4. The fluid management cassette system of claim 3 wherein the pathway is blocked when the valve element is moved fully into the channel.

5. The fluid management cassette system of claim 3 wherein the valve element is movable partially into the channel to effect a flow restriction in the pathway.

6. The fluid management cassette system of claim 1 wherein the first film and second film are disposable and replaceable.

7. The fluid management cassette system of claim 1 wherein the first film and second film are sealed about an extent of their peripheries so as to form a bag.

8. The fluid management cassette system of claim 1 wherein at least one of the first platen and second platen comprises a matrix of segments movable from an extended position toward the other of the first platen and second platen to a retracted position away from the other of the first platen and second platen with the channel formed by an arrangement of the segments in their retracted positions.

9. The fluid management cassette system of claim 8 where in a flow control valve in the channel comprises one or more of the segments moveable into the channel.

10. The fluid management cassette system of claim 1 and further comprising a fluid pump formed in at least one of the first and second platens.

11. The fluid management cassette system of claim 10 wherein the pump comprises a chamber along one of the one or more channels, a check valve forming an inlet from the one or more channel into the chamber and arranged to allow flow into the chamber, a pump element at the chamber arranged to apply pressure against one of the first and second films at the chamber whereby the pressure drives flow out of the chamber.

12. The fluid management cassette system of claim 10 wherein the pump comprises a positive displacement element movable along one of the one or more channels to effect a peristaltic pumping action.

13. A method of managing a fluid flow comprising:

trapping opposed first and second films between opposed first and second platens;

forming a fluid pathway between the first and second films via a channel formed into at least one of the first and second platens; and

flowing fluid through the pathway.

14. The method of claim 13 wherein the first and second films have surfaces at the pathway and said surfaces are sterile prior to the step of flowing fluid through the pathway.

15. The method of claim 13 and further comprising the step of impeding flow of fluid through the pathway by moving a valve element against at least one of the first and second films and into the channel to obstruct flow through the pathway.

16. The method of claim 15 wherein the movement of the valve element into the channel completely blocks flow through the pathway.

17. The method of claim 15 wherein the movement of the valve element into the channel partially blocks flow through the pathway.

18. The method of claim 13 wherein at least one of the first and second platens comprises a matrix of segments movable from an extended position toward the other of the first platen and second platen to a retracted position away from the other of the first platen and second platen and comprising the step of forming the channel by an arrangement of the segments in their retracted positions.

19. The method of claim 18 and further comprising pumping fluid along the channel by engaging segments along the channel in a wave pattern to induce flow along the channel.