SYSTEM AND METHOD FOR ESTIMATING AND MANIPULATING ESTIMATED RADIATION DOSE
First Claim
1. A method for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject, the achievable dose distribution estimate defined over a three-dimensional range of voxels with a dose value for each voxel, the method comprising:
- (a) determining a dose modification voxel for which it is desired to modify the dose value and determining a corresponding magnitude of desired dose modification;
(b) for each of a plurality of beams;
(i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing a projection of the beamlet into space; and
(ii) identifying one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel;
(c) modifying the intensity values of the identified dose-change beamlets based on the magnitude of desired dose modification, wherein modifying the intensity value of the identified dose-change beamlets comprises, for each of the identified dose-change beamlets, modifying the intensity value of the identified dose-change beamlet by a corresponding amount, the corresponding amount based on the magnitude of the desired dose modification; and
(d) updating the achievable dose distribution estimate to account for the modified intensity values of the identified dose-change beamlets.
2 Assignments
0 Petitions
Accused Products
Abstract
Methods are provided for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject. One such method comprises: determining a dose modification voxel for which it is desired to modify the dose value and a corresponding magnitude of desired dose modification; for each of a plurality of beams: (i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing the projection of the beamlet into space; and (ii) identifying one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel; modifying the intensity values of at least one of the dose-change beamlets; and updating the achievable dose distribution estimate to account for the modified intensity values of the at least one of the dose-change beamlets.
36 Citations
84 Claims
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1. A method for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject, the achievable dose distribution estimate defined over a three-dimensional range of voxels with a dose value for each voxel, the method comprising:
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(a) determining a dose modification voxel for which it is desired to modify the dose value and determining a corresponding magnitude of desired dose modification; (b) for each of a plurality of beams; (i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing a projection of the beamlet into space; and (ii) identifying one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel; (c) modifying the intensity values of the identified dose-change beamlets based on the magnitude of desired dose modification, wherein modifying the intensity value of the identified dose-change beamlets comprises, for each of the identified dose-change beamlets, modifying the intensity value of the identified dose-change beamlet by a corresponding amount, the corresponding amount based on the magnitude of the desired dose modification; and (d) updating the achievable dose distribution estimate to account for the modified intensity values of the identified dose-change beamlets. - View Dependent Claims (2, 7, 8, 9, 10, 11, 12, 13, 14, 20, 21, 22, 23, 29, 30, 31, 33, 34, 35, 36, 39, 40, 41, 43, 45, 46, 49, 50, 51, 52, 53, 54, 55, 56, 57, 60, 61, 62, 63, 64, 66)
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3-6. -6. (canceled)
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15-19. -19. (canceled)
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24-28. -28. (canceled)
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32. (canceled)
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37-38. -38. (canceled)
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42. (canceled)
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44. (canceled)
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47-48. -48. (canceled)
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58-59. -59. (canceled)
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65. A system for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject, the achievable dose distribution estimate defined over a three-dimensional range of voxels with a dose value for each voxel, the system comprising a controller configured to:
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determine a dose modification voxel for which it is desired to modify the dose value and a corresponding magnitude of desired dose modification; for each of a plurality of beams; characterize the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing a projection of the beamlet into space; and identify one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel; modify the intensity values of the identified dose-change beamlets based on the magnitude of the desired dose modification, wherein the controller is configured to modify the intensity value of the identified dose change beamlets by, for each of the identified dose-change beamlets, modifying the intensity value of the identified dose-change beamlet by a corresponding amount, the corresponding amount based on the magnitude of the desired dose modification; and update the achievable dose distribution estimate to account for the modified intensity values of the identified dose-change beamlets.
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67. A method for estimating a dose distribution over a three-dimensional range of voxels proposed to contain a subject resulting from one or more beams, each beam comprising a spatially varying two-dimensional intensity distribution characterized by a two-dimensional array of beamlets wherein each beamlet is associated with a corresponding intensity value, the method comprising, for each of the one or more beams:
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associating a ray line with each beamlet, the ray line representing a projection of the beamlet into space; convolving the two-dimensional intensity distribution with a two-dimensional dose estimate kernel to obtain a two-dimensional convolved intensity distribution, the two-dimensional convolved intensity distribution comprising a convolved intensity value for each beamlet; and for each beamlet in the two-dimensional array of beamlets;
identifying voxels in the three-dimensional range of voxels that are intersected by the ray line associated with the beamlet; and
adding a dose contribution to the intersected voxels, the added dose contribution based on the convolved intensity value of the beamlet. - View Dependent Claims (83)
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68-81. -81. (canceled)
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82. A system for estimating a dose distribution over a three-dimensional range of voxels proposed to contain a subject resulting from one or more beams, each beam comprising a spatially varying two-dimensional intensity distribution characterized by a two-dimensional array of beamlets wherein each beamlet is associated with a corresponding intensity value, the system comprising a controller configured to, for each of the one or more beams:
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associate a ray line with each beamlet, the ray line representing a projection of the beamlet into space; convolve the two-dimensional intensity distribution with a two-dimensional dose estimate kernel to obtain a two-dimensional convolved intensity distribution, the two-dimensional convolved intensity distribution comprising a convolved intensity value for each beamlet; and for each beamlet in the two-dimensional array of beamlets;
identify voxels in the three-dimensional range of voxels that are intersected by the ray line associated with the beamlet; and
add a dose contribution to the intersected voxels, the added dose contribution based on the convolved intensity value of the beamlet.
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84-88. -88. (canceled)
Specification