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METHOD AND APPARATUS FOR MEDICAL IMAGING USING COMBINED NEAR-INFRARED OPTICAL TOMOGRAPHY, FLUORESCENT TOMOGRAPHY AND ULTRASOUND

  • US 20130109963A1
  • Filed: 10/31/2011
  • Published: 05/02/2013
  • Est. Priority Date: 10/31/2011
  • Status: Abandoned Application
First Claim
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1. A method comprising:

  • obtaining an image of a tissue volume with a probe comprising;

    an ultrasound transducer that is operative to provide an on-site estimation of inclusion size and location;

    a first emitter and a first detector;

    the first emitter having light of a wavelength of about 400 to about 900 nanometers;

    the first detector detecting light of a wavelength of about 400 to about 900 nanometers;

    a source circuit connected in operational communication to the emitter;

    a detector circuit connected in operational communication to the detector; and

    a central processing unit connected to the source circuit and the detector circuit;

    scanning the tissue volume with light having a wavelength of about 400 to about 900 nanometers;

    the tissue volume comprising a first layer and a second layer;

    segmenting the scanned tissue volume into an inclusion region comprising a plurality of first voxels and a background region comprising a plurality of second voxels;

    the volume of each second voxel being larger than the volume of each first voxel;

    reconstructing the image using the equation (2)
    [Usd]

    1
    =[WL,WB]

    N
    ×

    [M
    L,MB]T

    1




    (2)where WL and WB are weight matrices for the inclusion and background regions, respectively;

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