EXPERT SYSTEM TO FACILITATE SOURCE LOCALIZATION OF BRAIN ELECTRICAL ACTIVITY
First Claim
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1. A computer-implemented system to localize a source of electrical activity in a patient'"'"'s body, the system comprising:
- a preprocessing component programmed to preprocess electrical data corresponding to electrical signals acquired from a patient;
an inverse model to represent the source of electrical activity;
a forward model to represent geometry and electrical characteristics of a spatial region of interest for the patient'"'"'s body based on the inverse model;
a source localization function programmed to compute a location for the source of electrical activity within the spatial region of interest based on the preprocessed electrical data, the inverse model and the forward model; and
an expert system to evaluate an acceptability of the computed location for the source of electrical activity and to selectively adjust of at least one of the preprocessing, the inverse model and the forward model based on the evaluation of the acceptability, the expert system adapted to cause the source localization function to re-compute the location for the source of electrical activity based on the selective adjustment.
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Abstract
A system or method can facilitate source localization of brain electrical activity. In one example, an expert system can be utilized to evaluate the source localization results and, based on the acceptability of the results, adjust a data preparation phase to provide for acceptable source localization.
39 Citations
21 Claims
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1. A computer-implemented system to localize a source of electrical activity in a patient'"'"'s body, the system comprising:
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a preprocessing component programmed to preprocess electrical data corresponding to electrical signals acquired from a patient; an inverse model to represent the source of electrical activity; a forward model to represent geometry and electrical characteristics of a spatial region of interest for the patient'"'"'s body based on the inverse model; a source localization function programmed to compute a location for the source of electrical activity within the spatial region of interest based on the preprocessed electrical data, the inverse model and the forward model; and an expert system to evaluate an acceptability of the computed location for the source of electrical activity and to selectively adjust of at least one of the preprocessing, the inverse model and the forward model based on the evaluation of the acceptability, the expert system adapted to cause the source localization function to re-compute the location for the source of electrical activity based on the selective adjustment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A non-transitory computer-readable medium having instructions which, when executed, cause a processor to:
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prepare brain electrical data acquired from a patient and geometry data; perform source localization based on the prepared brain electrical data and geometry data to determine a location of a source of electrical activity; implement an expert system to evaluate an acceptability of the source localization and to adjust at least one of the preparation of the brain electrical data and the geometry data if the acceptability of the source localization is not within a predetermined acceptability level; and store output data corresponding to the location of the source of electrical activity if the acceptability of the source localization is within the predetermined acceptability level. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21)
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Specification