MICROSTRUCTURED IMPLANT SURFACES

• US 20130110243A1
• Filed: 11/01/2011
• Published: 05/02/2013
• Est. Priority Date: 11/01/2011
• Status: Active Grant

• Current Assignee: Titan Spine, Inc. (Medtronic Plc)
• Original Assignee: Titan Spine, LLC
• Inventors: Berg, Mark, Ullrich, Peter, Schneider, Jennifer, Patterson, Chad
• Granted Patent: US 8,992,619 B2
• Time in Patent Office: Days
• US Class Current: 623/17.16
• CPC Class Codes: A61F 2/30767 Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
• CPC Class Codes: A61F 2/4455 for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages intervertebral discs A61F2/442
• CPC Class Codes: A61F 2/4465 having a circular or kidney shaped cross-section substantially perpendicular to the axis of the spine
• CPC Class Codes: A61F 2/4611 of spinal prostheses
• CPC Class Codes: A61F 2002/2817 Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
• CPC Class Codes: A61F 2002/2835 Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
• CPC Class Codes: A61F 2002/30011 differing in porosity
• CPC Class Codes: A61F 2002/30321 differing in roughness
• CPC Class Codes: A61F 2002/30451 soldered or brazed or welded
• CPC Class Codes: A61F 2002/30593 hollow
• CPC Class Codes: A61F 2002/30769 madreporic
• CPC Class Codes: A61F 2002/30774 internally-threaded
• CPC Class Codes: A61F 2002/30779 arcuate
• CPC Class Codes: A61F 2002/30785 parallel
• CPC Class Codes: A61F 2002/30787 inclined obliquely with respect to each other
• CPC Class Codes: A61F 2002/30789 perpendicular with respect to each other
• CPC Class Codes: A61F 2002/30838 Microstructures
• CPC Class Codes: A61F 2002/3084 Nanostructures
• CPC Class Codes: A61F 2002/30906 shot- sand- or grit-blasted
• CPC Class Codes: A61F 2002/3092 having an open-celled or open-pored structure
• CPC Class Codes: A61F 2002/30925 : etched
• CPC Class Codes: A61F 2002/3093 : for promoting ingrowth of bone tissue
• CPC Class Codes: A61F 2002/3097 : using laser
• CPC Class Codes: A61F 2002/30985 : using three dimensional printing [3DP]
• CPC Class Codes: A61F 2002/4629 : connected to the endoprosthesis or implant via a threaded connection
• CPC Class Codes: A61F 2310/00023 : Titanium or titanium-based alloys, e.g. Ti-Ni alloys
• CPC Class Codes: A61F 2310/00407 : Coating made of titanium or of Ti-based alloys
• CPC Class Codes: Y10S 977/81 : Of specified metal or metal alloy composition
• CPC Class Codes: Y10S 977/91 : Strengthening cell or tissue

Abstract

An implantable device for treating disc degenerative disease and arthritis of the spine. The implant is sized for placement into an intravertebral disc space. The implant has a body with a predetermined, defined, repeating, three-dimensional pattern at least partially on at least one of its surfaces. The pattern is adapted to create a surface area of bone-contacting features that enhance in-growth and biological attachment to a biocompatible material. Also disclosed are process steps for making the implant.

Claims

1. An implantable device comprising:

a body, the body having a surface and being sized for placement into an intravertebral disc space, the surface having a defined, repeating, three-dimensional pattern, the three-dimensional pattern resulting from the application to the surface of first and second two-dimensional surface patterns;

each said first and second patterns having a depth dimension, the first said pattern depth dimension being greater than the second depth dimension to create a surface area of bone-contacting features that allow for in-growth and biological attachment to a biocompatible material.

2. An implantable device according to claim 1 wherein the first and second two-dimensional patterns are non-overlapping.

3. An implantable device according to claim 1 wherein the surface is created by application to the surface of,

first, second, and third two dimensional surface patterns, each said first, second and third surface pattern also having a depth dimension, the depth dimension of the first pattern being greater than the second depth dimension and the second depth dimension being greater than the depth dimension.

4. An implantable device according to claim 3 wherein the first, second, and third two-dimensional patterns are non-overlapping.

5. The implantable device of claim 1 wherein the surface comprises multiple, two-dimensional overlapping patterns of varying depths and predefined orientation to have higher load resistance to a specific load direction without overloading bone tissues.

6. A method of making an implant device comprising:

providing an implant having a surface;

creating a first defined pattern on the surface;

adding a second defined pattern on the surface, the second defined pattern overlapping the first defined pattern; and

including at least one other defined pattern on the surface that overlaps with the first and second defined patterns.

7. An implantable prosthetic device adapted to promote osteointegration, the device comprising:

a body, the body having a surface, the surface having a defined three-dimensional pattern, the three-dimensional pattern resulting from the application to the surface of first and second two-dimensional surface patterns;

each said first and second patterns having a depth dimension, the first said pattern depth dimension being greater than the second depth dimension to create a surface area of bone-contacting features that allow for in-growth and biological attachment to a biocompatible material.

8. A device according to claim 7 wherein the two-dimensional surface patterns are non-overlapping.

9. A device according to claim 7 in which the surface has first, second, and third two-dimensional patterns.

10. A device according to claim 9 wherein the first, second, and third two-dimensional patterns are non-overlapping.