SURGICAL IMPLANT

• US 20130116793A1
• Filed: 07/25/2011
• Published: 05/09/2013
• Est. Priority Date: 07/23/2010
• Status: Active Grant

• Current Assignee: Privelop-Spine AG
• Original Assignee: Privelop-Spine AG
• Inventors: Kloss, Henning
• Granted Patent: US 10,245,152 B2
• Time in Patent Office: Days
• US Class Current: 623/17.16
• CPC Class Codes: A61F 2/30965 Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
• CPC Class Codes: A61F 2/442 Intervertebral or spinal discs, e.g. resilient non-disc-shaped intervertebral inflatable pockets A61F2/441; non-disc-shaped intervertebral fusion implants A61F2/4455
• CPC Class Codes: A61F 2/4455 for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages intervertebral discs A61F2/442
• CPC Class Codes: A61F 2/4465 having a circular or kidney shaped cross-section substantially perpendicular to the axis of the spine
• CPC Class Codes: A61F 2002/2817 Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
• CPC Class Codes: A61F 2002/30062 (bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
• CPC Class Codes: A61F 2002/3008 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 2002/30133 kidney-shaped or bean-shaped
• CPC Class Codes: A61F 2002/30143 hexagonal
• CPC Class Codes: A61F 2002/30146 octagonal
• CPC Class Codes: A61F 2002/30149 pentagonal
• CPC Class Codes: A61F 2002/30583 filled with hardenable fluid, e.g. curable in-situ
• CPC Class Codes: A61F 2002/30593 hollow
• CPC Class Codes: A61F 2002/30617 Visible markings for adjusting, locating or measuring
• CPC Class Codes: A61F 2002/30677 Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
• CPC Class Codes: A61F 2002/3092 having an open-celled or open-pored structure
• CPC Class Codes: A61F 2310/00017 Iron- or Fe-based alloys, e.g. stainless steel
• CPC Class Codes: A61F 2310/00023 Titanium or titanium-based alloys, e.g. Ti-Ni alloys
• CPC Class Codes: A61F 2310/00029 Cobalt-based alloys, e.g. Co-Cr alloys or Vitallium
• CPC Class Codes: A61F 2310/00089 Zirconium or Zr-based alloys
• CPC Class Codes: A61F 2310/00095 : Niobium or Nb-based alloys
• CPC Class Codes: A61F 2310/00101 : Molybdenum or Mo-based alloys
• CPC Class Codes: A61F 2310/00125 : Hafnium or Hf-based alloys
• CPC Class Codes: A61F 2310/00137 : Tungsten or W-based alloys
• CPC Class Codes: A61F 2310/00149 : Platinum or Pt-based alloys
• CPC Class Codes: A61F 2310/00155 : Gold or Au-based alloys
• CPC Class Codes: A61F 2310/00227 : containing titania or titanium oxide
• CPC Class Codes: A61F 2310/00239 : containing zirconia or zirconium oxide ZrO2

Abstract

The present invention is directed to a surgical implant for the fusion of two adjacent vertebrae with an upper plane for contacting an upper vertebral body and a lower plane for contacting a lower vertebral body and a tubular structure, wherein the tubular structure is formed by a plurality of tubes running from the upper plane to the lower plane and in substantially horizontal direction throughout one side of the surgical implant straight to the opposite side of the surgical implant. This tubular structure has the advantage that the formation and ingrowth of new bone is promoted and advantaged and that the degree of formation and ingrowth of new bone is detectable by X-ray measurements.

Claims

1-22. -22. (canceled)

23. A surgical implant with an upper plane for contacting an upper vertebral body and a lower plane for contacting a lower vertebral body and a tubular structure, wherein the tubular structure is formed by a plurality of tubes running from the upper plane to the lower plane and in substantially horizontal direction throughout one side of the surgical implant straight to the opposite side of the surgical implant and the tubes of the tubular structure are parallel to each other or the tubes of the tubular structure are grouped into groups of parallel tubes.

25. The surgical implant according to claim 23, wherein the boundary layer surrounds the at least one cavity completely also on the upper plane and the lower plane.

27. The surgical implant according to claim 23, wherein the implant comprises two, three, four, five or six cavities.

29. The surgical implant according to claim 23, wherein the boundary layer has a thickness of 1.5 mm to 10.0 mm.

31. The surgical implant according to claim 23, wherein the surgical implant has a porosity of at least 75%.

33. The surgical implant according to claim 23, wherein the ratio of the volume of cage material to the total surface area is between 200 μ

m and 230 μ

m.

35. The surgical implant according to claim 23, wherein the vertical tubes of the tubular structure extend substantially along the longitudinal axis of the spinal column.

37. The surgical implant according to claim 23, wherein between 10% and 90% of the tubes forming the tubular structure end at the cavity.

39. The surgical implant according to claim 23, wherein the bone replacement material is selected from polymeric bioresorbable materials, polymeric bioresorbable materials containing an osteoinductive agent, bioresorbable materials containing bone-forming cells or materials which are converted to new bone under physiologic conditions.

41. The surgical implant according to claim 23, wherein the vertical tubes and/or the horizontal tubes have a cross-sectional area of 50,000 μ

m² to 3,100,000 μ

m₂.

43. The surgical implant according to claim 23, wherein the tubes have a diameter of 250 μ

m to 2,000 μ

m.

45. The surgical implant according to claim 23, wherein the upper plane and the lower plane of the implant have at least 80 tubes per cm².

47. The surgical implant according to claim 23, wherein the vertical tubes and/or the horizontal tubes don'"'"'t change their inner diameter on their way through the implant.

49. The surgical implant according to claim 23, wherein the boundary layer is manufactured in one continuous piece.

51. The surgical implant according to claim 23, wherein the implant is selected from the group consisting of cervical cages, thoracic cages, lumbar cages, artificial intervertebral disks and implants for the fusion of natural and artificial vertebrae.

53. The surgical implant according to claim 23, wherein the ratio of the volume of the material of the boundary layer to the volume of the tubes ranges from 10 vol. %:

90 vol. % to 20 vol. %;

80 vol. %.

56. A kit comprising

the surgical implant according to claim 23 and

bone replacement material or bone cement or artificial bone material in an amount sufficient to fill the at least one cavity of the surgical implant.

57. The kit according to claim 56, further comprising at least one tool for filling the bone replacement material or bone cement or artificial bone material into the at least one cavity of the surgical implant

58. The kit according to claim 56, further comprising a textile-like material suitable for being impregnated with bone replacement material or artificial bone material.

24. A surgical implant with an upper plane for contacting an upper vertebral body and a lower plane for contacting a lower vertebral body, at least one cavity in the center of the implant and a boundary layer around the cavity with a tubular structure, wherein the tubular structure is formed by a plurality of tubes running from the upper plane to the lower plane and in horizontal direction or in substantially horizontal direction throughout one side of the surgical implant straight to the opposite side of the surgical implant and the tubes of the tubular structure are parallel to each other or the tubes of the tubular structure are grouped into groups of parallel tubes.

26. The surgical implant according to claim 24, wherein the boundary layer surrounds the at least one cavity completely also on the upper plane and the lower plane.

28. The surgical implant according to claim 24, wherein the implant comprises two, three, four, five or six cavities.

30. The surgical implant according to claim 24, wherein the boundary layer has a thickness of 1.5 mm to 10.0 mm.

32. The surgical implant according to claim 24, wherein the surgical implant has a porosity of at least 75%.

34. The surgical implant according to claim 24, wherein the ratio of the volume of cage material to the total surface area is between 200 μ

m and 230 μ

m.

36. The surgical implant according to claim 24, wherein the vertical tubes of the tubular structure extend substantially along the longitudinal axis of the spinal column.

38. The surgical implant according to claim 24, wherein between 10% and 90% of the tubes forming the tubular structure end at the cavity.

40. The surgical implant according to claim 24, wherein the bone replacement material is selected from polymeric bioresorbable materials, polymeric bioresorbable materials containing an osteoinductive agent, bioresorbable materials containing bone-forming cells or materials which are converted to new bone under physiologic conditions.

42. The surgical implant according to claim 24, wherein the vertical tubes and/or the horizontal tubes have a cross-sectional area of 50,000 μ

m² to 3,100,000 μ

m².

44. The surgical implant according to claim 24, wherein the tubes have a diameter of 250 μ

m to 2,000 μ

m.

46. The surgical implant according to claim 24, wherein the upper plane and the lower plane of the implant have at least 80 tubes per cm².

48. The surgical implant according to claim 24, wherein the vertical tubes and/or the horizontal tubes don'"'"'t change their inner diameter on their way through the implant.

50. The surgical implant according to claim 24, wherein the boundary layer is manufactured in one continuous piece.

52. The surgical implant according to claim 24, wherein the implant is selected from the group consisting of cervical cages, thoracic cages, lumbar cages, artificial intervertebral disks and implants for the fusion of natural and artificial vertebrae.

54. The surgical implant according to claim 24, wherein the ratio of the volume of the material of the boundary layer to the volume of the tubes ranges from 10 vol. %:

90 vol. % to 20 vol. %;

80 vol. %.

55. The surgical implant according to claim 24, wherein the ratio of the volume of the cavity to the overall volume of the implant ranges from 1:

2 to 1;

1.

59. A kit comprising

the surgical implant according to claim 24 and

bone replacement material or bone cement or artificial bone material in an amount sufficient to fill the at least one cavity of the surgical implant.

60. The kit according to claim 59, further comprising at least one tool for filling the bone replacement material or bone cement or artificial bone material into the at least one cavity of the surgical implant

61. The kit according to claim 59, further comprising a textile-like material suitable for being impregnated with bone replacement material or artificial bone material.