DETECTION DEVICE AND DETECTION METHOD FOR INTERMOLECULAR INTERACTION
First Claim
1. A detection device for an intermolecular interaction, comprising:
- a detector having a ligand;
a white light source emitting white light;
a spectrometer to detect a spectral intensity of received light;
a light transmission unit including a first optical transmission path for transmitting the white light from the white light source to the detector, a second optical transmission path for transmitting reflected light of the white light from the detector to the spectrometer and a third optical transmission path for transmitting the white light from the white light source to the spectrometer;
a switching unit switching between a reflected light receiving state which allows the reflected light of the white light at the detector to be transmitted to the spectrometer via the second optical transmission paths and a white light receiving state which allows the white light from the white light source to be transmitted to the spectrometer via the third optical transmission path; and
a controller controlling the switching unit and the spectrometer to detect the spectral intensities in the white light receiving state and in the reflected light receiving state.
2 Assignments
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Accused Products
Abstract
In order to improve the detection accuracy of a reflection spectrum, a detection device for intermolecular interaction is provided with a detector (10) which has a ligand (16), a white light source (20) which emits white light, a spectroscope (30) which detects the spectral intensity of received light, a light transmission unit (40) which has a first light transmission path (41) for transmitting the white light from the white light source to the detector, a second light transmission path (42) for transmitting reflected light of the white light from the detector to the spectroscope, and a third light transmission path (43) for transmitting the white light from the white light source to the spectroscope, a switching unit (80) which performs switching between a reflected light receiving state in which the transmission of the reflected light of the white light in the detector to the spectroscope via the first and second light transmission paths is enabled and a white light receiving state in which the transmission of the white light from the white light source to the detector via the third light transmission path is enabled, and a control unit (50) which controls the switching unit and the spectroscope to perform control for detecting the spectral intensities in the white light receiving state and the reflected light receiving state, respectively.
9 Citations
5 Claims
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1. A detection device for an intermolecular interaction, comprising:
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a detector having a ligand; a white light source emitting white light; a spectrometer to detect a spectral intensity of received light; a light transmission unit including a first optical transmission path for transmitting the white light from the white light source to the detector, a second optical transmission path for transmitting reflected light of the white light from the detector to the spectrometer and a third optical transmission path for transmitting the white light from the white light source to the spectrometer; a switching unit switching between a reflected light receiving state which allows the reflected light of the white light at the detector to be transmitted to the spectrometer via the second optical transmission paths and a white light receiving state which allows the white light from the white light source to be transmitted to the spectrometer via the third optical transmission path; and a controller controlling the switching unit and the spectrometer to detect the spectral intensities in the white light receiving state and in the reflected light receiving state. - View Dependent Claims (2, 3, 4)
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5. A detection method for detecting an intermolecular interaction using a detection device comprising a detector having a ligand, a white light source emitting white light, a spectrometer detecting spectral intensity of received light, a light transmission unit including a first optical transmission path for transmitting the white light from the white light source to the detector, a second optical transmission path for transmitting reflected light of the white light from the detector to the spectrometer and a third optical transmission path for transmitting the white light from the white light source to the spectrometer, the method comprising:
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a first detection step of receiving the reflected light of the white light from the detector via the first and the second optical transmission paths and detecting the spectral intensity of the reflected light by the spectrometer; a second detection step of receiving the white light from the white light source via the third optical transmission path either before or after the first detection step and detecting the spectral intensity of the white light by the spectrometer; and a calculation step of estimating a reflection spectrum by calculating a reflectance for every predetermined wavelength range on a basis of the spectral intensities of the white light and the reflected light obtained in the first detection step and the second detection step.
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Specification