COMPOSITIONS COMPRISING A SHELF-LIFE STABILITY COMPONENT

• US 20130129869A1
• Filed: 11/23/2011
• Published: 05/23/2013
• Est. Priority Date: 11/23/2011
• Status: Abandoned Application

• Current Assignee: Proteus Digital Health, Inc. (Otsuka Holdings Company Limited)
• Original Assignee: Proteus Digital Health, Inc. (Otsuka Holdings Company Limited)
• Inventors: Hafezi, Hooman, Schmidt, Raymond, Ching, Ai Ling
• Application Number:
  US13/304,260
• Publication Number:
  US 20130129869A1
• Time in Patent Office: Days
• US Class Current: 426/89
• CPC Class Codes: A23L 3/00 Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs preserving foods or foodstuffs in association with packaging B65B55/00
• CPC Class Codes: A23L 3/3427 in which an absorbent is placed or used packages for foodstuffs with provision for absorbing fluids B65D81/26
• CPC Class Codes: A61B 5/073 Intestinal transmitters
• CPC Class Codes: H04B 1/0343 to be carried on the body

Abstract

Compositions that include a shelf-life stability component are provided. In some instances, the compositions are ingestible compositions which include the shelf-life stability component and an ingestible component. Aspects of the invention further include methods of making and using the compositions.

Claims

1. A composition comprising a shelf-life stability component physically associated with a minimally dimensioned component.

2. The composition according to claim 1, wherein the composition is an ingestible composition comprising the shelf-life stability component and an ingestible component physically associated with the ingestible composition.

3. The ingestible composition according to claim 2, wherein the composition further comprises an ingestible device.

4. The ingestible composition according to claim 3, wherein the ingestible device is an ingestible event marker.

5. The composition according to claim 1, wherein the ingestible composition is stable for 1 year or longer under conditions in which the temperature ranges from 10 to 40°

C., the pressure ranges from 0.5 to 2.0 ATM and the relative humidity ranges from 10 to 100%.

6. The composition according to claim 1, wherein the shelf-life stability component comprises a water-vapor desensitizer.

7. The composition according to claim 5, wherein the water-vapor desensitizer comprises a protective barrier that rapidly disrupts upon contact with a liquid.

8. The composition according to claim 7, wherein the protective barrier comprises a homogeneous layer of a single material.

9. The composition according to claim 7, wherein the protective barrier comprises two or more distinct materials.

10. The composition according to claim 9, wherein the two or more distinct materials are present as a single homogeneous or heterogeneous layer.

11. The composition according to claim 9, wherein the two or more distinct materials are present as a multilayer structure.

12. The composition according to claim 9, wherein the two or more distinct materials exhibit different aqueous medium solubility.

13. The composition according to claim 9, wherein the two or more distinct materials exhibit different aqueous medium physical properties.

14. The composition according to claim 9, wherein the two or more distinct materials comprise a first material and a second material that solubilizes the first material.

15. The composition according to claim 7, wherein the protective barrier comprises a lipid.

16. The composition according to claim 7, wherein the protective barrier comprises a low-melting point material.

17. The composition according to claim 7, wherein the protective barrier is a galvanic protective barrier.

18. The composition according to claim 7, wherein the protective barrier is configured to be disruptable by a device present in the composition.

19. The composition according to claim 7, wherein the protective barrier is configured to provide aqueous liquid passage through the protective barrier upon contact of ingestible composition with an aqueous liquid.

20. The composition according to claim 7, wherein the protective barrier comprises a liquid passageway.

21. The composition according to claim 6, wherein the water-vapor desensitizer comprises a desiccant.

22. The composition according to claim 1, wherein minimally dimensioned component is a micro-battery.

23. A system comprising:

an ingestible composition comprising;

a shelf-life stability component; and

an ingestible component associated with the shelf-life stability component; and

a receiver configured to receive a communication associated with the ingestible composition.

24. A method comprising combining a minimally dimensioned component and a shelf-life stability component.

25. The method according to claim 24, wherein the minimally dimensioned component is an ingestible component and the method produces an ingestible composition.

26. The method according to claim 25, wherein the method comprises stably associating the ingestible component and the shelf-life stability component.

27. The method according to claim 26, wherein the method comprises one or more protocols selected from the group consisting of laminating, pressing, stamping, extruding, molding and coating.

28. The method according to claim 27, wherein at least a portion of the method is automated.