METHODS AND DEVICES FOR DIAGNOSING AND TREATING VOCAL CORD DYSFUNCTION

• US 20130131551A1
• Filed: 03/24/2011
• Published: 05/23/2013
• Est. Priority Date: 03/24/2010
• Status: Abandoned Application

• Current Assignee: Purdue Research Foundation (Purdue University)
• Original Assignee: Purdue Research Foundation (Purdue University)
• Inventors: Raghunathan, Shriram, Kelly, Marc, Hagen, Jessica, Abdel-Latief, Omar
• Application Number:
  US13/636,919
• Publication Number:
  US 20130131551A1
• Time in Patent Office: Days
• US Class Current: 600/587
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/1107 Measuring contraction of parts of the body, e.g. organ, muscle apparatus for measuring work or force in general G01L
• CPC Class Codes: A61B 5/394 specially adapted for electroglottography or electropalatography
• CPC Class Codes: A61N 1/0456 Specially adapted for transcutaneous electrical nerve stimulation [TENS]
• CPC Class Codes: A61N 1/0472 Structure-related aspects
• CPC Class Codes: A61N 1/0476 Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
• CPC Class Codes: A61N 1/048 Electrodes characterised by a specific connection between lead and electrode
• CPC Class Codes: A61N 1/0492 Patch electrodes A61N1/0412, A61N1/0428 take precedence
• CPC Class Codes: A61N 1/0526 Head electrodes A61N1/0551 takes precedence
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/3601 of respiratory organs
• CPC Class Codes: A61N 1/3603 Control systems

Abstract

Methods for diagnosing and treating vocal cord dysfunction by recording the position of the vocal cords of a subject during a monitoring period are disclosed. Portable devices are disclosed using electronic signals to provide diagnostic data indicating a subject'"'"'s closed or open vocal cords to diagnose and treat vocal cord dysfunction. Corresponding software and circuitry are also disclosed.

Claims

1. A device supported by a subject or by an investigator, the device using electronic signals to provide diagnostic data indicating an area of opening between vocal folds of vocal cords of subject, whether vocal folds of vocal cords are opened or closed as an indication of vocal cord dysfunction, the device comprising:

a power source,

a signal generator powered by the power source, the signal generator configured to generate electronic signals,

a microcontroller configured to transmit, direct, or control the passage of electronic signals,

at least one pair of electrodes, the at least one pair of electrodes configured to be disposed adjacent to the vocal cords of the subject, the at least one pair of vocal cords including a first electrode configured to be disposed to one side of the vocal cords and a second electrode configured to be disposed to the other side of the vocal cords, wherein the transmission of electronic signals between the at least one pair of electrodes and through the vocal cords of the subject provides diagnostic data indicating an open position or a closed position of the subject'"'"'s vocal cords, and

memory configured to record diagnostic data.

2. The device of claim 1 further comprising a strap configured to fit around the neck of the subject, the strap configured to fit adjacent to the vocal cords of the subject, the strap including a fastener, the strap configured to support the power source, the signal generator, the microcontroller, the at least one pair of electrodes and memory.

3. The device of claim 2, wherein the strap is configured to locate the at least one pair of electrodes adjacent to the vocal cords of the subject.

4. The device of claim 1, wherein the device is a hand held unit supported by the subject, the investigator, or a caregiver.

5. The device of claim 1 further comprising a user trigger, a sensor, and a stimulator coupled to the power source, wherein the stimulator is configured to stimulate of the recurrent laryngeal nerve of the patient causing opening of the vocal cords of the patient.

6. The device of claim 1, wherein the at least one pair of electrodes is supported by a detachable flap.

7. The device of claim 6, wherein the detachable flap includes connectors to connect the detachable flap with the signal generator and the microcontroller, the connectors configured to transmit electronic signals to and from the at least one pair of electrodes.

8. The device of claim 1, further comprising a microphone coupled to the memory, the microphone configured to record sounds from the subject in conjunction with the diagnostic data.

9. A method of diagnosing vocal cord dysfunction by recording the position of the vocal cords of a subject during a monitoring period, the method comprises the steps of:

evaluating a subject for asthma or vocal cord dysfunction,

providing the subject with a recording device which measures the area of opening between vocal folds of the vocal cords, the device including at least one pair of electrodes configured to be disposed on opposite sides of the vocal cords of the subject,

monitoring the subject for a period of time,

transmitting electronic signals between the at least one pair of electrodes,

recording data indicating an open position or a closed position of the subject'"'"'s vocal cords during the monitoring period of time, and

analyzing data to diagnose vocal cord dysfunction.

10. The method of claim 9 further comprising the step of treating the subject with vocal cord dysfunction by stimulating a nerve which causes opening of the vocal cords.

11. The method of claim 9 further comprising the step of recording the position of the vocal cords of the subject during a period of airflow obstruction during the monitoring period of time.

12. The method of claim 9 further comprising the step of transmitting data to an external machine.

13. The method of claim 9 wherein the device includes a collar to support the device on the subject.

14. The method of claim 13 wherein the step of providing the subject with the recording device further comprises the step of fitting the subject with the recording device, wherein the recording device is configured to fit around to the neck of the subject.

15. The method of claim 9 wherein the device is a hand held unit supported by the subject, an investigator, or a caregiver.

16. The method of claim 15 wherein the step of providing the subject with the recording device further comprises the step of fitting the subject with at least a portion of the recording device, wherein the portion of the recording device is configured to be disposed adjacent to the vocal cords of the subject.

17. A device using electronic signals to provide diagnostic data indicating a subject'"'"'s closed or open vocal cords during vocal cord dysfunction, the device comprising:

a signal generator configured to generate a sinusoidal AC voltage waveform,

a voltage-to-current converter configured to generate a constant current amplitude and alternating voltage,

a switch configured to couple the constant current amplitude and alternating voltage to an electrode,

a pair of electrodes configured to transmit the constant current amplitude and alternating voltage across the vocal cords of the subject,

a root-mean-square detector to measure the relative impedance across the vocal cords,

a microcontroller configured to transmit, direct or digitize the measured relative impedance, and

memory configured to store electronic signals.

18. The device of claim 17 further comprising a phase measurement component for comparison against the measured relative impedance.

19. The device of claim 17 further comprising a calibration module coupled to the microcontroller by the switch.

20. The device of claim 17 further comprising an interface which allows for stored electronic signals to be downloaded.