Functionalized Membrane For A Chamber For Encapsulating Cells Producing At Least One Substance Of Therapeutic Interest And Bioartificial Organ Comprising Such A Membrane
First Claim
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1. A functionalized semi-permeable membrane for the production of a chamber for encapsulating secretory cells of a bioartificial organ composed of a porous biocompatible support, wherein:
- said porous biocompatible support is pretreated so that its surface energy is greater than or equal to 50 mJ·
m−
2;
the pores of said porous biocompatible support have an inner size between 5 and 100 nm, andsaid functionalized semi-permeable membrane comprises at least two layers each comprising a hydrophilic polymer and at least one biologically active molecule.
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Abstract
The present invention relates to a functionalized semi-permeable membrane composed of a porous biocompatible support pretreated so as to increase the surface energy thereof and characterized in that it comprises at least two layers, each comprising a hydrophilic polymer and at least one biologically active molecule, and to the use thereof in particular for producing a bioartificial organ.
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10 Claims
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1. A functionalized semi-permeable membrane for the production of a chamber for encapsulating secretory cells of a bioartificial organ composed of a porous biocompatible support, wherein:
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said porous biocompatible support is pretreated so that its surface energy is greater than or equal to 50 mJ·
m−
2;the pores of said porous biocompatible support have an inner size between 5 and 100 nm, and said functionalized semi-permeable membrane comprises at least two layers each comprising a hydrophilic polymer and at least one biologically active molecule. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification