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METHODS AND SYSTEMS FOR CONVERTING PRECURSOR CELLS INTO INTESTINAL TISSUES THROUGH DIRECTED DIFFERENTIATION

  • US 20130137130A1
  • Filed: 05/06/2011
  • Published: 05/30/2013
  • Est. Priority Date: 05/06/2010
  • Status: Active Grant
First Claim
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1. A method of inducing formation of an intestinal tissue, comprising:

  • activating one or more signaling pathways within a precursor cell, wherein said one or more signaling pathways are selected from the group consisting of the Wnt signaling pathway, Wnt/APC signaling pathway, FGF signaling pathway, TGF-beta signaling pathway, shh signaling pathway, BMP signaling pathway, Notch signaling pathway, Hedgehog signaling pathway, LKB signaling pathway, and Par polarity signaling pathway; and

    obtaining an intestinal tissue descended from said precursor cell.

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