VASCULAR IMPLANT AND DELIVERY SYSTEM

• US 20130138207A1
• Filed: 01/31/2013
• Published: 05/30/2013
• Est. Priority Date: 04/15/2009
• Status: Active Grant

• Current Assignee: Edwards Lifesciences CardiAQ LLC (Edwards Lifesciences Corporation)
• Original Assignee: Cardiaq Valve Technologies Incorporated (Edwards Lifesciences Corporation)
• Inventors: Quadri, Arshad, Ratz, J. Brent
• Granted Patent: US 9,339,379 B2
• Time in Patent Office: Days
• US Class Current: 623/2.18
• CPC Class Codes: A61F 2/0805 Implements for inserting tendons or ligaments
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/243 Deployment by mechanical expansion
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/2439 Expansion controlled by filaments
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2/9522 Means for mounting a stent or stent-graft onto or into a placement instrument
• CPC Class Codes: A61F 2002/0882 Anchor in or on top of a bone tunnel, i.e. a hole running through the entire bone
• CPC Class Codes: A61F 2002/9534 for repositioning of stents
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2250/001 for adjusting a diameter

Abstract

A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.

Claims

1. A prosthesis configured to grasp intraluminal tissue when deployed within a body cavity, the prosthesis comprising:

an expandable frame comprising a proximal end and a distal end, the frame configured to radially expand and contract for deployment within the body cavity, wherein when the frame is in an expanded configuration, the frame has a larger cross-sectional dimension in a first portion of the frame and a smaller cross-sectional dimension in a second portion of the frame, wherein the first portion is proximal to the second portion; and

a plurality of proximally-extending anchors extending from the second portion of the frame and configured so that when the frame is in an expanded configuration each anchor is positioned radially outward from the second portion of the frame, wherein the frame is configured such that radial expansion of the frame causes the ends of the plurality of proximally-extending anchors to draw closer to the proximal end of the frame;

wherein the frame is further configured such that when in an expanded configuration, an area is defined between the ends of the plurality of anchors and a first portion of the prosthesis for capturing tissue there between.

2. The prosthesis of claim 1, wherein the second portion is at the distal end of the frame.

3. The prosthesis of claim 2, wherein the first portion is at the proximal end of the frame.

4. The prosthesis of claim 2, wherein the first portion is located in a middle portion of the frame.

5. The prosthesis of claim 1, wherein when the frame is in an expanded configuration, a shoulder is defined by the transition between the first portion of the frame and the second portion of the frame.

6. The prosthesis of claim 5, wherein when the frame is in an expanded configuration, the frame has a substantially constant outer diameter from the proximal end to the shoulder.

7. The prosthesis of claim 5, wherein when the frame is in an expanded configuration, the ends of the plurality of proximally-extending anchors are disposed diametrically about the same as or outwardly from the shoulder.

8. The prosthesis of claim 1, wherein the plurality of proximally-extending anchors extend from a foreshortening portion of the frame.

9. The prosthesis of claim 1, further comprising a plurality of distally-extending anchors extending from the first portion of the frame and configured such that radial expansion of the frame causes the ends of the proximally-extending anchors and the ends of the distally-extending anchors to draw closer together.

10. The prosthesis of claim 9, wherein the plurality of distally-extending anchors extend from a non-foreshortening portion of the frame.

11. The prosthesis of claim 1, further comprising a valve body attached to the frame.