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Anti-Interferent Barrier Layers for Non-Invasive Transdermal Sampling and Analysis Device

  • US 20130144142A1
  • Filed: 11/29/2012
  • Published: 06/06/2013
  • Est. Priority Date: 12/02/2011
  • Status: Active Grant
First Claim
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1. A transdermal sampling and analysis device comprising:

  • a substrate having a first side;

    at least one disruptor mounted on the first side of the substrate, wherein the at least one disruptor is configured to generate a localized heat capable of altering permeability characteristics of a stratum corneum layer of skin of an organism;

    a reservoir configured to collect and contain a biological sample; and

    a biological sensing element comprising at least two sensing electrodes configured, to determine levels of an analyte in the biological sample, wherein;

    a surface of at least one of the sensing electrodes is coated with a sensing layer having a first charge type; and

    the sensing layer is covered with an anti-interferent barrier layer having at least a second charge type, wherein the first charge type is an opposite charge type from the second charge type.

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