CLOT CAPTURE SYSTEMS AND ASSOCIATED METHODS

• US 20130144326A1
• Filed: 10/26/2012
• Published: 06/06/2013
• Est. Priority Date: 07/22/2008
• Status: Active Grant

• Current Assignee: Neuravi Limited (Johnson & Johnson)
• Original Assignee: Neuravi Limited (Johnson & Johnson)
• Inventors: Brady, Eamon, Vale, David, Razavi, Mahmood, O'Shaughnessy, John, Gilvarry, Michael
• Granted Patent: US 9,402,707 B2
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0008 elliptical or oval
• CPC Class Codes: A61F 2230/001 Figure-8-shaped, e.g. hourglass-shaped
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0058 X-shaped

Abstract

A clot capture system for disengaging a clot from a vessel wall and removing the clot from the vessel, comprises a clot capture device for placement on a distal side of a clot. The clot capture device has a retracted delivery configuration and an expanded deployed configuration. The clot removal device has a proximal support frame, and a distal fibre net. The support frame has a retracted delivery configuration and an expanded deployed configuration. The proximal support frame in the expanded configuration defines a proximal inlet mouth for engaging a clot and a net for confining the clot. An elongate member facilitates capture and/or withdrawal of a clot from a vessel.

Claims

1. A clot removal device for restoring blood flow to a vessel occluded by an obstructive clot, the device having an expanded deployed configuration, and a retracted delivery configuration in which it may be advanced through a microcatheter across said obstructive clot, and the device configured such that upon deployment at least a part of the device is deployed distal to the clot and at least a portion is deployed proximal to the clot, the device comprising:

—

a frame, a net and a shaft,

the frame comprising at least two struts and at least one crown, and,

the frame also comprising at least one connector element, the proximal end of the at least one connector element being connected to the shaft,

the frame comprising a cylindrical section in the expanded configuration, said cylindrical section being configured to engage with a clot, and the net being configured to confine at least a portion of a clot.

2. A clot removal device as claimed in claim 1 wherein the shaft comprises an inner member and an outer member which are movable relative to one another to assist the expansion of the frame.

3. A clot removal device as claimed in claim 1 wherein the shaft comprises an elongate member which is movable relative to the frame.

4. A clot removal device as claimed in claim 1 wherein the frame in the expanded configuration defines at least one inlet mouth for engaging a clot.

5. A clot removal device as claimed in claim 1 wherein the shaft is extendable proximally exterior of a patient and wherein movement of the shaft causes movement of a captured clot.

6. A clot removal device for restoring blood flow to a vessel occluded by an obstructive clot, the device having an expanded deployed configuration, and a retracted delivery configuration in which it may be advanced through a microcatheter across said obstructive clot, the device being configured such that upon deployment, at least a part of the device is deployed distal to the clot and at least a portion is deployed proximal to the clot, the device comprising:

—

a shaft, a proximal section and a distal section,

a distal end of said shaft being attached to a proximal end of said proximal section,

said proximal section comprising an axially extending portion, a radially extending portion and a circumferentially extending portion.

said proximal section also comprising at least two struts and at least one crown,

and said distal section comprising a net,

the net being configured to confine at least a portion of a clot.

7. A clot removal device as claimed in claim 6 wherein the shaft comprises art elongate member which is movable relative to the proximal section.

8. A clot removal device as claimed in claim 6 wherein the proximal section in the expanded configuration defines at least one inlet mouth for engaging a clot.

9. A clot removal device as claimed in claim 6 wherein the shaft is extendable proximally exterior of a patient and wherein movement of the shaft causes movement of a captured clot.

10. A clot removal device as claimed in claim 6 wherein the net comprises at least one fibre of less than 25 microns in diameter.

11. A method for removing an obstruction from a vessel comprising providing a clot retrieval device, the device comprising an elongate member having a capture frame and capture net affixed thereto, the capture frame having a collapsed configuration and an expanded configuration and the elongate member comprising an inner member and an outer member,

the method further comprising the steps of:

advancing the device with the capture frame in the collapsed configuration across the obstruction;

moving the inner member relative the outer member to support the expansion of the frame;

advancing the device proximally to capture the obstruction; and

removing the clot retrieval device from the patient.

12. A method for removing an obstruction from a vessel comprising providing a clot retrieval device, the device comprising an elongate member having a capture frame affixed there to, the capture frame having a collapsed configuration and an expanded configuration, the elongate member comprising a shaft and a guidewire,

the method further comprising the steps of:

advancing the device with the capture frame in the collapsed configuration across the obstruction;

deploying the device across the obstruction;

retracting the device shaft to move the capture frame proximally to capture and withdraw some or all of the obstruction whilst leaving the guidewire in position to retain access to the vessel; and

removing the clot retrieval device from the patient.

13. A method as claimed in claim 12 wherein the device is advanced over the guidewire and through a microcatheter to cross the obstruction.