System and Method for Image Sequence Processing
First Claim
1. A method of refining a feature associated with an image, comprising:
- receiving at least one time-aligned pair of images of a heart, wherein each at least one time-aligned pair of images comprises a rest image and a stressed image, wherein the rest image comprises an image of the heart at a particular point in time in the cardiac cycle of the heart when the heart is at rest and the stressed image comprises an image of the heart at the particular point in time in the cardiac cycle of the heart when the heart is under a stress stimulus, wherein each stressed image of the at least one time-aligned pair of images has a feature associated therewith, wherein the feature comprises at least one point wherein each at least one point has a position in the stressed image; and
refining the position of one or more points in the feature associated with the stressed image of one or more of the at least one time-aligned pair of images based on information derived from the rest image of one or more of the at least one time-aligned pair of images.
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Abstract
A method for processing a sequence of images. In an embodiment, one or more training datasets are analyzed having a sequence of images showing a first condition and a sequence of images showing a second condition. A multivariate regression model is used to determine a relationship between relative positions of one or more features in the sequence of images showing the first condition and relative positions of the one or more features in the sequence of images showing the second condition. In an embodiment, the determined relationship is used to predict positions of the one or more features in an inquire sequence of images showing the second condition given an inquire sequence of images showing the first condition. The predicted positions can then be refined using various methods. In an embodiment, sequences of images are aligned to a common time scale.
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Citations
26 Claims
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1. A method of refining a feature associated with an image, comprising:
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receiving at least one time-aligned pair of images of a heart, wherein each at least one time-aligned pair of images comprises a rest image and a stressed image, wherein the rest image comprises an image of the heart at a particular point in time in the cardiac cycle of the heart when the heart is at rest and the stressed image comprises an image of the heart at the particular point in time in the cardiac cycle of the heart when the heart is under a stress stimulus, wherein each stressed image of the at least one time-aligned pair of images has a feature associated therewith, wherein the feature comprises at least one point wherein each at least one point has a position in the stressed image; and refining the position of one or more points in the feature associated with the stressed image of one or more of the at least one time-aligned pair of images based on information derived from the rest image of one or more of the at least one time-aligned pair of images. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method of temporally aligning a plurality of images of a heart, comprising:
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identifying in a plurality of images of a heart at least three phase images corresponding to a corresponding at least three phases of a cardiac cycle of the heart, wherein the plurality of images comprises images of the heart at a corresponding plurality of timepoints within the cardiac cycle of the heart, wherein the plurality of images are sequenced in the order of their corresponding timepoints within the cardiac cycle of the heart; and assigning a time value to each image of the plurality of images, wherein the at least three phase images are assigned time values based on an established timing of their corresponding phases in the cardiac cycle of the heart and the remaining images of the plurality of images are assigned time values based on at least two piecewise interpolation functions, wherein for each consecutive pair of phase images of the at least three phase images a suitable programmed computer applies one of the at least two piecewise interpolation functions to the images sequenced between the consecutive pair of phase images to determine the assigned time values of the images based on the time values assigned to the consecutive pair of phase images. - View Dependent Claims (13)
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14. One or more non-transitory computer-readable media having computer-useable instructions embodied thereon for performing a method of refining a feature associated with an image, the method comprising:
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receiving at least one time-aligned pair of images of a heart, wherein each at least one time-aligned pair of images comprises a rest image and a stressed image, wherein the rest image comprises an image of the heart at a particular point in time in the cardiac cycle of the heart when the heart is at rest and the stressed image comprises an image of the heart at the particular point in time in the cardiac cycle of the heart when the heart is under a stress stimulus, wherein each stressed image of the at least one time-aligned pair of images has a feature associated therewith, wherein the feature comprises at least one point wherein each at least one point has a position in the stressed image; and refining the position of one or more points in the feature associated with the stressed image of one or more of the at least one time-aligned pair of images based on information derived from the rest image of one or more of the at least one time-aligned pair of images. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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25. One or more non-transitory computer-readable media having computer-useable instructions embodied thereon for performing a method of temporally aligning a plurality of images of a heart, the method comprising:
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identifying in a plurality of images of a heart at least three phase images corresponding to a corresponding at least three phases of a cardiac cycle of the heart, wherein the plurality of images comprises images of the heart at a corresponding plurality of timepoints within the cardiac cycle of the heart, wherein the plurality of images are sequenced in the order of their corresponding timepoints within the cardiac cycle of the heart; and assigning a time value to each image of the plurality of images, wherein the at least three phase images are assigned time values based on an established timing of their corresponding phases in the cardiac cycle of the heart and the remaining images of the plurality of images are assigned time values based on at least two piecewise interpolation functions, wherein for each consecutive pair of phase images of the at least three phase images a suitable programmed computer applies one of the at least two piecewise interpolation functions to the images sequenced between the consecutive pair of phase images to determine the assigned time values of the images based on the time values assigned to the consecutive pair of phase images. - View Dependent Claims (26)
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Specification