NEURAL INTERFACE DEVICE AND INSERTION TOOLS

• US 20130172717A1
• Filed: 12/21/2012
• Published: 07/04/2013
• Est. Priority Date: 12/22/2011
• Status: Active Grant

• Current Assignee: Modular Bionics, Inc.
• Original Assignee: Modular Bionics, Inc.
• Inventors: Halpern, Ian Loren, Merlo, Mark William
• Granted Patent: US 9,095,267 B2
• Time in Patent Office: Days
• US Class Current: 600/378
• CPC Class Codes: A61B 2560/0219 of externally powered implanted units
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/291 for electroencephalography [EEG]
• CPC Class Codes: A61B 5/685 Microneedles
• CPC Class Codes: A61N 1/0502 Skin piercing electrodes
• CPC Class Codes: A61N 1/0529 Electrodes for brain stimulation
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor

Abstract

An implanted neural micro interface device is provided. The device comprises microfilaments of various materials and forms embedded within a body. The microfilaments form interaction sites with surrounding neural tissue at their exit points from the implantable body. The body and filaments are configurable in a multitude of positions to provide increased engagement of a given neural tissue section as well as interaction and closed loop feedback between the microfilament sites. Such configurations allow for a range of recording, stimulating, and treatment modalities for the device within research and clinical settings.

Claims

1. A neural microarray, comprising:

a base member;

a plurality of elongate shafts extending from the base member, the elongate shafts each having a sidewall, a channel therethrough; and

a plurality of sites in communication with the channel and spaced apart along the sidewall, the sites configured to stimulate tissue or record a tissue parameter; and

a plurality of microfilaments housed within the channel of the plurality of elongate shafts and extending proximally from at least the base member and at least one of the microfilaments each extending distally out each of the plurality of sites.

2. The microarray of claim 1, wherein the base member is flexible.

3. The microarray of claim 1, further comprising at least one site disposed on a surface of the base member.

4. The microarray of claim 1, wherein the base member comprises a hinged portion.

5. The microarray of claim 1, wherein the sites are configured such that the microfilaments extending distally out of each of the plurality of exit ports are configured to be movable in at least 6 degrees of freedom when inserted in or proximate neural tissue.

6. The microarray of claim 1, wherein the sites are spaced axially apart along longitudinal axes of the shafts.

7. The microarray of claim 1, wherein the shafts comprise a helical shape.

8. The microarray of claim 1, wherein the shafts comprise a proximal non-linear portion and a distal linear portion.

9. The microarray of claim 1, wherein the proximal non-linear portion is curved.

10. The microarray of claim 1, further comprising a power source operably connected to the microfilaments.

11. The microarray of claim 1, wherein the power source is wirelessly connectable to the microfilaments.

12. The microarray of claim 1, further comprising an amplifier operably connected to the microfilaments.

13. The microarray of claim 1, wherein the base member has a major axis that is transverse to the major axis of the plurality of the elongate shafts, wherein a thickness dimension of the base member parallel to the major axis of the plurality of the elongate shafts is no more than about 10 times the average diameter of the plurality of microfilaments.

14. (canceled)

15. (canceled)

16. A method for modulating neural activity, comprising:

providing a microarray comprising a plurality of shafts comprising magnetic coils;

inserting at least a portion of the shafts comprising the magnetic coils into neural tissue; and

activating the magnetic coils sufficiently to modulate neural activity.

17. (canceled)

18. (canceled)

19. (canceled)

20. (canceled)

21. (canceled)

22. (canceled)

23. (canceled)

24. (canceled)

25. A method of modulating neural activity, comprising:

providing a microarray comprising a first shaft and a second shaft, the first and second shaft each having a sidewall and at least one sidewall opening, the first and second shafts each comprising at least one conductive microfilament within a channel of the shafts such that a distal end of the microfilament is proximate the sidewall opening;

inserting the first shaft within tissue such that the sidewall opening is within tissue at a first location;

inserting the second shaft at a second position within tissue such that the sidewall opening is within tissue at a second location; and

activating the microfilaments,

wherein following activation of the microfilaments, a constructive energy field effect is created within a zone of target tissue by the coordinating of the microfilaments.

26. The method of claim 25, wherein the tissue is in the vicinity of the target tissue.

27. The method of claim 25, wherein the tissue is bone of the skull, and the target tissue is brain tissue.

28. The method of claim 25, wherein the tissue and the target tissue both comprise neural tissue.

29. (canceled)

30. (canceled)

31. (canceled)

32. (canceled)

33. (canceled)

34. (canceled)

35. (canceled)

36. (canceled)

37. (canceled)

38. (canceled)

39. (canceled)

40. (canceled)

41. (canceled)

42. (canceled)

43. (canceled)