ACCURATE FLOW CONTROL IN DRUG PUMP DEVICES
First Claim
Patent Images
1. A high-pressure drug pump device comprising:
- a drug reservoir;
an exit member for fluidically connecting the reservoir with a drug injection site;
a flow restrictor for restricting fluid flow through the exit member, the flow restrictor having a flow resistance factor of at least 106 μ
l−
1;
an electrolysis pump comprising a pump chamber in mechanical communication with the drug reservoir via an intervening displacement member, the electrolysis pump being operable to exert a pressure of at least 5 psi to drive the displacement member toward the exit member and thereby force therethrough fluid in the drug reservoir; and
circuitry for operating the pump to generate a pressure of at least 5 psi, the circuitry and the flow restrictor cooperating to cause continuous fluid flow through the exit member at a constant flow rate in the range from about 400 nl/min to about 5 μ
l/min.
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Accused Products
Abstract
The accuracy of drug delivery with drug pump devices may be improved by a combination of pump operation at high flow resistances and pump pressures, pressure-relief mechanisms, and sensor-based feedback for pump control.
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Citations
20 Claims
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1. A high-pressure drug pump device comprising:
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a drug reservoir; an exit member for fluidically connecting the reservoir with a drug injection site; a flow restrictor for restricting fluid flow through the exit member, the flow restrictor having a flow resistance factor of at least 106 μ
l−
1;an electrolysis pump comprising a pump chamber in mechanical communication with the drug reservoir via an intervening displacement member, the electrolysis pump being operable to exert a pressure of at least 5 psi to drive the displacement member toward the exit member and thereby force therethrough fluid in the drug reservoir; and circuitry for operating the pump to generate a pressure of at least 5 psi, the circuitry and the flow restrictor cooperating to cause continuous fluid flow through the exit member at a constant flow rate in the range from about 400 nl/min to about 5 μ
l/min. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification