Intrinsic Frequency Hemodynamic Waveform Analysis
First Claim
1. A system for acquiring and analyzing a hemodynamic waveform of a subject, the system comprising:
- an optical scanner, the scanner adapted to capture a signal corresponding to a hemodynamic waveform; and
at least one computer processor connected to the scanner by a wired or wireless connection, wherein the computer processor is adapted to receive the signal for the hemodynamic waveform, determine a Dicrotic Notch using the signal, calculate first and second intrinsic frequencies (ω
1, ω
2) on each side of the Dicrotic Notch for the waveform, and output a signal corresponding to intrinsic frequencies results.
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Abstract
Hardware and software methodology are described for cardiac health measurement. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. The intrinsic frequencies provide metrics/measures that correlate to the cardiac health of the subject. The systems may be used for monitoring a condition and/or is diagnosis. Exemplary uses include identifying (diagnosing) the presence of arrhythmia, heat failure, atrial fibrillation, aneurysms, vessel stenosis or aortic valve dysfunction and the necessity for valve replacement and/or monitoring congestive heart failure progression, together with identifying the acute need for hospitalization in connection with daily testing for any such condition.
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Citations
30 Claims
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1. A system for acquiring and analyzing a hemodynamic waveform of a subject, the system comprising:
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an optical scanner, the scanner adapted to capture a signal corresponding to a hemodynamic waveform; and at least one computer processor connected to the scanner by a wired or wireless connection, wherein the computer processor is adapted to receive the signal for the hemodynamic waveform, determine a Dicrotic Notch using the signal, calculate first and second intrinsic frequencies (ω
1, ω
2) on each side of the Dicrotic Notch for the waveform, and output a signal corresponding to intrinsic frequencies results. - View Dependent Claims (5, 6, 7, 8, 9)
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2. A system for acquiring and analyzing a hemodynamic waveform of a subject, the system comprising:
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an ultrasound scanner, the scanner adapted to capture a signal corresponding to a hemodynamic waveform; and at least one computer processor connected to the scanner by a wired or wireless connection, wherein the computer processor is adapted to receive the signal for the hemodynamic waveform, determine a Dicrotic Notch using the signal, calculate first and second intrinsic frequencies (ω
1, ω
2) on each side of the Dicrotic Notch for the waveform, and output a signal corresponding to intrinsic frequencies results.
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3. A system for acquiring and analyzing a hemodynamic waveform of a subject, the system comprising:
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a tonomeric scanner, the scanner adapted to capture a signal corresponding to a hemodynamic waveform; and at least one computer processor connected to the scanner by a wired or wireless connection, wherein the computer processor is adapted to receive the signal for the hemodynamic waveform, determine a Dicrotic Notch using the signal, calculate first and second intrinsic frequencies (ω
1, ω
2) on each side of the Dicrotic Notch for the waveform, and output a signal corresponding to intrinsic frequencies results.
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4. A system for acquiring and analyzing a hemodynamic waveform of a subject, the system comprising:
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a microwave scanner, the scanner adapted to capture a signal corresponding to a hemodynamic waveform; and at least one computer processor connected to the scanner by a wired or wireless connection, wherein the computer processor is adapted to receive the signal for the hemodynamic waveform, determine a Dicrotic Notch using the signal, calculate first and second intrinsic frequencies (ω
1, ω
2) on each side of the Dicrotic Notch for the waveform, and output a signal corresponding to intrinsic frequencies results.
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10. A computer readable medium having stored thereon instructions, which when executed cause one or more processors to:
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receive an input signal corresponding to a hemodynamic waveform; determine a Dicrotic Notch using the input signal, calculate first and second intrinsic frequencies on each side of the Dicrotic Notch for the waveform; and output a signal corresponding to the intrinsic frequencies.
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11. A computer-implemented method of analyzing a signal, comprising:
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inputting a hemodynamic waveform data for a subject, the waveform including a Dicrotic Notch; determining a position of the Dicrotic Notch in the waveform for dividing the signal into first and second sections for analysis; analyzing each of the first and second sections of the waves by to determine first and second intrinsic frequencies (ω
1, ω
2) where each intrinsic frequency is at or about a frequency that carries the highest energy for all frequencies of an instantaneous frequency curve; andoutputting a result of the analyzing. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification