SYSTEM AND DATA PROCESSING DEVICE FOR BIOIMPEDANCE ANALYSIS

• US 20130184605A1
• Filed: 05/10/2012
• Published: 07/18/2013
• Est. Priority Date: 01/13/2012
• Status: Abandoned Application

• Current Assignee: National Chi Nan University
• Original Assignee: Tak-Shing Ching
• Inventors: Sun, Tai-Ping, Ching, Tak-shing, Liu, Wei-Hao
• Application Number:
  US13/468,892
• Publication Number:
  US 20130184605A1
• Time in Patent Office: Days
• US Class Current: 600/547
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence

Abstract

A system for bioimpedance analysis of a biological tissue includes a tissue inspector and an impedance calculator. The tissue inspector includes an inspecting circuit for receiving a test signal, a plurality of electrode sets respectively corresponding with a plurality of test parts, and a multiplexer operable to couple a selected electrode set at a detected test part to the inspecting circuit to detect a signal response resulting from the test signal. The impedance calculator is operable to compute impedance information corresponding to the detected test part based on the test signal and the detected signal response.

Claims

1. A system for bioimpedance analysis of a biological tissue, said system comprising:

a tissue inspector including;

an inspecting circuit for receiving a test signal;

a plurality of electrode sets disposed to respectively correspond with a plurality of test parts of the biological tissue; and

a multiplexer operable to couple a selected one of said electrode sets corresponding to a detected one of the test parts to said inspecting circuit, wherein a signal response at the detected one of the test parts and resulting from the test signal is detected using the selected one of said electrode sets; and

an impedance calculator for computing impedance information corresponding to the detected one of the test parts based on the test signal and the signal response detected using the selected one of said electrode sets.

2. The system as claimed in claim 1, wherein each of said electrode sets includes a first electrode and a second electrode, said inspecting circuit including:

a resistor disposed to receive the test signal; and

an amplifier having an input coupled to said resistor, and an output;

wherein, when said multiplexer couples the selected one of said electrode sets to said inspecting circuit, said first electrode of the selected one of said electrode sets is coupled to said input of said amplifier through said multiplexer, said second electrode of the selected one of said electrode sets is coupled to said output of said amplifier through said multiplexer, the test signal is applied to the detected one of the test parts through said resistor and said first electrode, and the signal response includes a voltage between said first and second electrodes of the selected one of said electrode sets.

3. The system as claimed in claim 2, further comprising:

a differential amplifier having a first input coupled to said input of said amplifier of said inspecting circuit, and a second input coupled to said output of said amplifier of said inspecting circuit, said differential amplifier being operable to acquire the signal response of the detected one of the test parts according to signals at said first and second inputs thereof; and

an analog-to-digital converter operable to convert the signal response acquired by said differential amplifier into a digital response signal that is provided to said impedance calculator for computing the impedance information.

4. The system as claimed in claim 3, further comprising:

a first buffer coupled between said input of said amplifier and said first input of said differential amplifier; and

a second buffer coupled between said output of said amplifier and said second input of said differential amplifier.

5. The system as claimed in claim 1, further comprising a controller operable to control said multiplexer to couple the selected one of said electrode sets to said inspecting circuit, and operable to generate a coordinate signal corresponding to a location of the detected one of the test parts on the biological tissue.

6. The system as claimed in claim 5, further comprising an image generator operable to generate an image signal according to the impedance information and the coordinate signal that correspond to the detected one of the test parts.

7. The system as claimed in claim 6, wherein:

said image generator is configured to obtain a maximum value H and a minimum value L among the impedance information for the test parts of the biological tissue;

when a value M associated with a normal impedance range of the biological tissue is closer to the maximum value H than the minimum value L, said image generator is configured to generate grayscale values G according to G=D/[(H−

M)/(0.5R−

1)], wherein D represents the impedance information, and R represents a total number of grayscale levels; and

when the value M associated with the normal impedance range of the biological tissue is closer to the minimum value L than the maximum value H, said image generator is configured to generate the grayscale values G according to G=D/[(M−

L)/(0.5R−

1)].

8. The system as claimed in claim 7, wherein the value M associated with the normal impedance range of the biological tissue is an average of upper and lower limits of the normal impedance range of the biological tissue.

9. The system as claimed in claim 7, wherein said image generator is configured to generate the image signal according to the grayscale values G and the coordinate signals that correspond to the test parts of the biological tissue.

10. The system as claimed in claim 7, further comprising a judging unit operable to determine whether or not the biological tissue is normal according to the grayscale values and the coordinate signals that correspond to the test parts of the biological tissue.

11. The system as claimed in claim 1, wherein the signal response at the detected one of the test parts is an alternating current signal, and said impedance calculator is configured to compute the impedance information by obtaining a direct current (DC) component of the signal response, followed by dividing the DC component by a reference value related to the test signal.

12. The system as claimed in claim 11, wherein the signal response at the detected one of the test parts has a plurality of positive peak values and negative peak values, and the DC component is an average of the positive and negative peak values.

13. A data processing device adapted to receive a plurality of digital response signals that respectively correspond to a plurality of test parts of a biological tissue, said data processing device comprising:

an impedance calculator for computing impedance information of each of the test parts based on the digital response signal corresponding thereto;

an image generator operable to generate an image signal according to the impedance information from said impedance calculator and coordinate signals corresponding to respective locations of the test parts on the biological tissue; and

a judging unit operable to determine whether or not the biological tissue is normal according to the impedance information and the coordinate signals that correspond to the test parts of the biological tissue.

14. The data processing device as claimed in claim 13, further comprising a display for displaying an image corresponding to the image signal.

15. The data processing device as claimed in claim 13, wherein:

said image generator is configured to obtain a maximum value H and a minimum value L among the impedance information for the test parts of the biological tissue;

when a value M associated with a normal impedance range of the biological tissue is closer to the maximum value H than the minimum value L, said image generator is configured to generate grayscale values G according to G=D/[(H−

M)/(0.5R−

1)], wherein D represents the impedance information, and R represents a total number of grayscale levels; and

when the value M associated with the normal impedance range of the biological tissue is closer to the minimum value L than the maximum value H, said image generator is configured to generate the grayscale values G according to G=D/[(M−

L)/(0.5R−

1)].

16. The data processing device as claimed in claim 15, wherein the value M associated with the normal impedance range of the biological tissue is an average of upper and lower limits of the normal impedance range of the biological tissue.

17. The data processing device as claimed in claim 15, wherein said image generator is configured to generate the image signal according to the grayscale values G and the coordinate signals that correspond to the test parts of the biological tissue.