THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE
First Claim
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1. A compound of formula I or a pharmaceutically acceptable salt, tautomer, isotopologue or hydrate thereof, wherein:
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Abstract
Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
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18 Claims
- 1. A compound of formula I or a pharmaceutically acceptable salt, tautomer, isotopologue or hydrate thereof, wherein:
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12. The compound is selected from any one of compounds from Table 1.
Specification