SELECTIVE HIGH FREQUENCY SPINAL CORD MODULATION FOR INHIBITING PAIN, INCLUDING CEPHALIC AND/OR TOTAL BODY PAIN WITH REDUCED SIDE EFFECTS, AND ASSOCIATED SYSTEMS AND METHODS

• US 20130204324A1
• Filed: 03/14/2013
• Published: 08/08/2013
• Est. Priority Date: 09/08/2011
• Status: Active Grant

• Current Assignee: Nevro Corporation
• Original Assignee: Nevro Corporation
• Inventors: Thacker, James R., Alataris, Konstantinos, Gliner, Bradford Evan
• Granted Patent: US 9,283,387 B2
• Time in Patent Office: Days
• US Class Current: 607/46
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor
• CPC Class Codes: A61N 1/06 for high-frequency therapy
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36075 Headache or migraine
• CPC Class Codes: A61N 1/36157 Current A61N1/3616 takes precedence
• CPC Class Codes: A61N 1/3616 Voltage density or current density
• CPC Class Codes: A61N 1/36171 Frequency
• CPC Class Codes: A61N 1/36175 Pulse width or duty cycle
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration

Abstract

Selective high-frequency spinal chord modulation for inhibiting pain with reduced side affects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient'"'"'s spinal cord region from an epidural, cervical location to address at least one of high back pain, mid-back pain, low back pain, and leg pain without creating paresthesia in the patient.

Claims

1. A method of treating an upper extremity pain with a spinal cord modulation system, comprising:

implanting one or more signal delivery devices proximate to a target location at a patient'"'"'s spinal cord region;

coupling the one or more signal delivery devices to a signal generator; and

configuring the signal generator to generate and deliver an upper extremity pain therapy signal to the target location, via the one or more implanted signal delivery devices, without generating paresthesia;

wherein at least a portion of the therapy signal is at a frequency in a frequency range of from about 1.5 kHz to about 100 kHz.

2. The method of claim 1, wherein the target location is a cervical vertebral location.

3. The method of claim 2, wherein the cervical vertebral location is between C2-C6, inclusive.

4. The method of claim 2, wherein the cervical vertebral location is between C3-C5, inclusive.

5. The method of claim 1, wherein the upper extremity pain is selected from the group consisting of:

arthritis pain, acromio-clavicular joint pain, fibromyalgia pain in the shoulders or arms, myofascial pain in the shoulders or arms, subdeltoid bursitis pain, bicipital tendonitis pain, supraspinatus pain, rotator cuff tear pain, deltoid pain, teres major pain, scapulocostal pain, tennis elbow pain, golfer'"'"'s elbow pain, anconeus pain, supinator pain, pain due to ulnar nerve entrapment at the elbow, lateral antebrachial cutaneous nerve pain, olecranon bursitis pain, and phantom limb pain.

6. The method of claim 1, wherein the frequency range is from about 3 kHz to about 20 kHz.

7. The method of claim 1, wherein the frequency range is from about 5 kHz to about 15 kHz.

8. The method of claim 1, wherein the one or more signal delivery devices include a percutaneous lead having one or more electrodes disposed toward a distal end of the percutaneous lead.

9. A method of treating an upper extremity pain, comprising:

applying an electrical therapy signal to a cervical vertebral location at a patient'"'"'s spinal cord, wherein at least a portion of the electrical therapy signal is at a frequency in a frequency range of from about 1.5 kHz to about 100 kHz, and wherein the electrical therapy signal treats the upper extremity pain without generating paresthesia in the patient.

10. The method of claim 9, wherein the cervical vertebral location is between C2-C6, inclusive.

11. The method of claim 9, wherein the cervical vertebral location is between C3-C5, inclusive.

12. The method of claim 9, wherein the upper extremity pain is selected from the group consisting of:

arthritis pain, acromio-clavicular joint pain, fibromyalgia pain in the shoulders or arms, myofascial pain in the shoulders or arms, subdeltoid bursitis pain, bicipital tendonitis pain, supraspinatus pain, rotator cuff tear pain, deltoid pain, teres major pain, scapulocostal pain, tennis elbow pain, golfer'"'"'s elbow pain, anconeus pain, supinator pain, pain due to ulnar nerve entrapment at the elbow, lateral antebrachial cutaneous nerve pain, olecranon bursitis pain, and phantom limb pain.

13. The method of claim 9, wherein the frequency range is from about 3 kHz to about 20 kHz.

14. The method of claim 9, wherein the frequency range is from about 5 kHz to about 15 kHz.

15. The method of claim 9, further comprising:

implanting one or more signal delivery devices proximate to the cervical vertebral location, wherein the electrical therapy signal is applied to the cervical vertebral location via the one or more signal delivery devices.

16. The method of claim 15, further comprising:

coupling the one or more implanted signal delivery devices to an implanted signal generator, wherein the signal generator is programmed with instructions that, when executed, treat the upper extremity pain by generating and delivering the electrical therapy signal to the cervical vertebral location.

17. The method of claim 15, wherein the one or more signal delivery devices include a percutaneous lead having one or more electrodes disposed toward a distal end of the percutaneous lead.

18. An upper extremity pain treatment system, comprising:

a spinal cord modulation system having

at least one signal delivery device configured to be implanted proximate to a cervical vertebral location in a patient'"'"'s spinal cord, and

a signal generator programmed with instructions that, when executed, treat an upper extremity pain by generating and delivering a non-paresthesia-generating electrical therapy signal to the cervical vertebral location, via the at least one signal delivery device,

wherein at least a portion of the electrical therapy signal is at a frequency in a frequency range of from about 1.5 kHz to about 100 kHz.

19. The system of claim 18, wherein the cervical vertebral location is between C2-C6, inclusive.

20. The system of claim 18, wherein the cervical vertebral location is between C3-C5, inclusive.

21. The system of claim 18, wherein the upper extremity pain is selected from the group consisting of:

arthritis pain, acromio-clavicular joint pain, fibromyalgia pain in the shoulders or arms, myofascial pain in the shoulders or arms, subdeltoid bursitis pain, bicipital tendonitis pain, supraspinatus pain, rotator cuff tear pain, deltoid pain, teres major pain, scapulocostal pain, tennis elbow pain, golfer'"'"'s elbow pain, anconeus pain, supinator pain, pain due to ulnar nerve entrapment at the elbow, lateral antebrachial cutaneous nerve pain, olecranon bursitis pain, and phantom limb pain.

22. The system of claim 18, wherein the frequency range is from about 3 kHz to about 20 kHz.

23. The system of claim 18, wherein the frequency range is from about 5 kHz to about 15 kHz.

24. The system of claim 18, wherein the at least one signal delivery device includes a percutaneous lead having one or more electrodes disposed toward a distal end of the percutaneous lead.

25. The system of claim 18, wherein the electrical therapy signal includes one or more pulses with a pulse width between about 10 microseconds and about 333 microseconds.

26. The system of claim 18, wherein the electrical therapy signal includes one or more pulses with a pulse width between about 25 microseconds and about 166 microseconds.