ANTISENSE NUCLEIC ACIDS
First Claim
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1. An antisense oligomer which causes skipping of the 53rd exon in the human dystrophin gene, consisting of a nucleotide sequence complementary to any one of the sequences consisting of the 32nd to the 56th or the 36th to the 56th nucleotides from the 5′
- end of the 53rd exon in the human dystrophin gene.
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Abstract
The present invention provides a pharmaceutical composition which causes skipping of the 53rd exon in the human dystrophin gene with a high efficiency.
The present invention provides an oligomer which efficiently enables to cause skipping of the 53rd exon in the human dystrophin gene.
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Citations
14 Claims
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1. An antisense oligomer which causes skipping of the 53rd exon in the human dystrophin gene, consisting of a nucleotide sequence complementary to any one of the sequences consisting of the 32nd to the 56th or the 36th to the 56th nucleotides from the 5′
- end of the 53rd exon in the human dystrophin gene.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 12, 13, 14)
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9-11. -11. (canceled)
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