Probe Device and a Method of Fabricating the Same

• US 20130211485A1
• Filed: 02/13/2013
• Published: 08/15/2013
• Est. Priority Date: 02/13/2012
• Status: Abandoned Application

• Current Assignee: Agency For Science Technology and Research
• Original Assignee: Agency For Science Technology and Research
• Inventors: GOVINDARAJAN, Anupama Vijay, TAY, Guang Kai Ignatius, PARK, Woo-Tae
• Application Number:
  US13/766,042
• Publication Number:
  US 20130211485A1
• Time in Patent Office: Days
• US Class Current: 607/116
• CPC Class Codes: A61B 2562/028 Microscale sensors, e.g. electromechanical sensors [MEMS]
• CPC Class Codes: A61B 2562/125 characterised by the manufacture of electrodes
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/6868 Brain
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: Y10T 156/10 Methods of surface bonding and/or assembly therefor

Abstract

According to embodiments of the present invention, a probe device is provided. The probe device includes a flexible probe that is implantable into a biological tissue, a rigid carrier, and a biodegradable material received in a recess defined between the flexible probe and the rigid carrier, the biodegradable material bonding the flexible probe and the rigid carrier to each other, wherein the biodegradable material is dissolvable in the biological tissue such that the flexible probe and the rigid carrier are separable and the rigid carrier is removable from the biological tissue, and wherein the biodegradable material is capable of drug delivery upon dissolution. According to further embodiments of the present invention, a method of fabricating a probe device is also provided.

Claims

1. A probe device comprising:

a flexible probe that is implantable into a biological tissue;

a rigid carrier; and

a biodegradable material received in a recess defined between the flexible probe and the rigid carrier, the biodegradable material bonding the flexible probe and the rigid carrier to each other, wherein the biodegradable material is dissolvable in the biological tissue such that the flexible probe and the rigid carrier are separable and the rigid carrier is removable from the biological tissue, and wherein the biodegradable material is capable of drug delivery upon dissolution.

2. The probe device of claim 1, wherein the recess is formed in a material of the flexible probe.

3. The probe device of claim 1, wherein the biodegradable material is selected from the group consisting of polyethylene glycol, polysaccharide, sugar candy and any combination thereof.

4. The probe device of claim 1, wherein the flexible probe comprises a polymeric material.

5. The probe device of claim 4, wherein the polymeric material is selected from the group consisting of Parylene, polyimide, polydimethylsiloxane, poly(methyl methacrylate), silicone, and SU-8.

6. The probe device of claim 1, wherein the rigid carrier comprises a material selected from the group consisting of silicon, titanium, and glass.

7. The probe device of claim 1, wherein the biodegradable material further comprises drugs and/or steroids that are releasable on the dissolution of the biodegradable material.

8. The probe device of claim 1, wherein the flexible probe comprises:

at least one electrode arranged at an insertion end of the flexible probe; and

at least one contact pad electrically coupled to the electrode, the contact pad being configured for electrical coupling to an external circuit.

9. The probe device of claim 8, wherein the flexible probe further comprises at least one interconnection buried within the flexible probe, the interconnection electrically coupling the electrode and the contact pad.

10. The probe device of claim 1, wherein the probe device comprises a plurality of flexible probes, wherein the biodegradable material is received in a respective recess defined between a respective flexible probe and the rigid carrier, the biodegradable material bonding the respective flexible probe and the rigid carrier to each other.

11. A method of fabricating a probe device, the method comprising:

forming a flexible probe that is implantable into a biological tissue;

forming a rigid carrier; and

bonding the flexible probe and the rigid carrier to each other with a biodegradable material between the flexible probe and the rigid carrier, wherein the biodegradable material is received in a recess defined between the flexible probe and the rigid carrier, wherein the biodegradable material is dissolvable in the biological tissue such that the flexible probe and the rigid carrier are separable, and wherein the biodegradable material is capable of drug delivery upon dissolution.

12. The method of claim 11, wherein the recess is formed in a material of the flexible probe.

13. The method of claim 11, further comprising:

forming a pair of sacrificial tracks between the flexible probe and the rigid carrier prior to bonding the flexible probe and the rigid carrier.

14. The method of claim 13, further comprising:

removing the pair of sacrificial tracks after bonding the flexible probe and the rigid carrier.

15. The method of claim 11, further comprising thermally bonding or microwave assisted bonding the flexible probe and the rigid carrier.

16. The method of claim 11, further comprising:

adding drugs and/or steroids within the biodegradable material, the drugs and/or steroids being releasable on the dissolution of the biodegradable material.

17. A probe device comprising:

a flexible probe that is implantable into a biological tissue;

a rigid carrier; and

polyethylene glycol or sugar candy between the flexible probe and the rigid carrier bonding the flexible probe and the rigid carrier to each other, in which the polyethylene glycol or the sugar candy is dissolvable in the biological tissue such that the flexible probe and the rigid carrier are separable and the rigid carrier is removable from the biological tissue.

18. The probe device of claim 17, wherein the polyethylene glycol or the sugar candy is received in a recess defined between the flexible probe and the rigid carrier.

19. The probe device of claim 18, wherein the recess is formed in a material of the flexible probe.

20. The probe device of claim 17, wherein the flexible probe comprises Parylene and the rigid carrier comprises silicon.