INHALER TO DELIVER SUBSTANCES FOR PROPHYLAXIS OR PREVENTION OF DISEASE OR INJURY CAUSED BY THE INHALATION OF BIOLOGICAL OR CHEMICAL AGENTS
First Claim
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1. A dry powder inhaler, comprising:
- a powder storage region that is configured to hold a powdered medicament effective for treating exposure to particular biological and chemical agents;
an inlet channel;
a dispersion chamber that is adapted to receive air and the powdered medicament from the inlet channel, the chamber holding an actuator that is movable within the dispersion chamber; and
an outlet channel through which air and aerosolized medicament exit the inhaler to be delivered to a patient;
wherein a geometry of the inhaler is such that a flow profile is generated within the dispersion chamber that causes the actuator to oscillate, thus enabling the actuator when oscillating to deaggregate the powdered medicament within the dispersion chamber to be aerosolized and entrained by the air and delivered to the patient through the outlet channel.
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Abstract
A dry powder inhaler may include a powder storage region, an inlet channel, a dispersion chamber, and an outlet channel. A geometry of the inhaler may be such that a flow profile is generated within the dispersion chamber that causes an actuator to oscillate, enabling the actuator when oscillating to deaggregate powdered medicament within the dispersion chamber to be aerosolized and entrained by the air and delivered to a patient through the outlet channel.
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Citations
23 Claims
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1. A dry powder inhaler, comprising:
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a powder storage region that is configured to hold a powdered medicament effective for treating exposure to particular biological and chemical agents; an inlet channel; a dispersion chamber that is adapted to receive air and the powdered medicament from the inlet channel, the chamber holding an actuator that is movable within the dispersion chamber; and an outlet channel through which air and aerosolized medicament exit the inhaler to be delivered to a patient; wherein a geometry of the inhaler is such that a flow profile is generated within the dispersion chamber that causes the actuator to oscillate, thus enabling the actuator when oscillating to deaggregate the powdered medicament within the dispersion chamber to be aerosolized and entrained by the air and delivered to the patient through the outlet channel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A dry powder inhaler system, comprising:
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a receptacle containing an amount of powdered medicament effective for treating exposure to particular biological and chemical agents; an inlet channel that is adapted to receive air from an air source and powdered medicament from the receptacle; a chamber that is adapted to receive air and powdered medicament from the inlet channel;
an actuator movably held within the chamber; andan outlet channel through which air and aerosolized medicament leave the chamber to be delivered to a patient; wherein the geometry of the system is such that a flow profile is generated within the system that causes the actuator to oscillate, thus enabling the oscillating actuator to effectively disperse powdered medicament passing through the chamber to be aerosolized and entrained by the air and delivered to the patient through the outlet channel. - View Dependent Claims (13, 14, 15, 16)
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17. A method for aerosolizing a powdered medicament, comprising:
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providing an inhaler comprising an inlet channel, a chamber in fluid communication with the inlet channel, an actuator disposed in the chamber, and an outlet channel through which air and aerosolized medicament exit the inhaler to be delivered to a patient; providing a powdered medicament effective for treating exposure to biological and chemical agents to the inlet channel; and inducing air to flow through the outlet channel to cause the actuator to oscillate within the chamber to deaggregate the powdered medicament within the chamber to be aerosolized and entrained by the air and delivered to the patient through the outlet channel. - View Dependent Claims (18, 19, 20, 21, 22, 23)
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Specification