PROCESS FOR MAKING MULTIPARTICULATE GASTRORETENTIVE DOSAGE FORMS
First Claim
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1. A process for making low density particles, comprising the steps of:
- (i) providing a powder mixture comprising a swelling agent;
(ii) granulating the powder of step (i) with a granulating solution comprising a lipophilic agent into granules;
(iii) drying the granules of step (ii).
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Abstract
The instant invention relates to a process for making inherent low density particles, comprising the steps of (i) providing a powder mixture comprising a swelling agent; (ii) granulating the powder of step (i) with a granulating solution comprising a lipophilic agent into granules and (iii) drying the granules of step (ii). The instant invention further relates to multiparticulate oral gastro-retentive dosage forms comprising the inherent low density particles obtainable by the process.
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15 Claims
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1. A process for making low density particles, comprising the steps of:
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(i) providing a powder mixture comprising a swelling agent; (ii) granulating the powder of step (i) with a granulating solution comprising a lipophilic agent into granules; (iii) drying the granules of step (ii). - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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Specification