DEVICES AND METHODS FOR DELIVERY OF AGENTS TO BIOLOGICAL TISSUE
First Claim
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1. A medical device, comprising:
- a reservoir configured to hold an agent, the reservoir comprising a release port that facilitates delivery of the agent to a biological tissue and an impermeable portion that is impermeable to release of the agent; and
a sealable base connected to the reservoir, the sealable base comprising an attachment mechanism that facilitates an attachment to the biological tissue.
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Abstract
Described herein are systems, apparatuses, and methods that employ a medical device to augment delivery of an agent to biological tissue. The medical device includes a reservoir containing the agent, a release port, and sealable base that can be attached to the biological tissue so that the agent is held under pressure upon attachment. The device can only release the agent through the release port. A penetrating instrument can be utilized to augment delivery of the agent to the biological tissue.
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Citations
21 Claims
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1. A medical device, comprising:
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a reservoir configured to hold an agent, the reservoir comprising a release port that facilitates delivery of the agent to a biological tissue and an impermeable portion that is impermeable to release of the agent; and a sealable base connected to the reservoir, the sealable base comprising an attachment mechanism that facilitates an attachment to the biological tissue. - View Dependent Claims (2, 3, 4, 5, 6, 9, 10, 11, 12, 13, 14)
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7. The medical device of claim 7, wherein the injection port is covered by a material that allows penetration with a penetrating instrument.
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8. The medical device of claim 8, wherein the injection port is self-sealing upon removal of the penetrating instrument.
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15. A method, comprising:
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attaching a sealable base of a device to a biological tissue, wherein the device comprises a reservoir containing an agent under pressure, the sealable base, an injection port, and a release port; penetrating the device through the injection port, the reservoir and the release port with a penetrating instrument; penetrating the biological tissue with the penetrating instrument; and removing the penetrating instrument from the biological tissue and the medical device, augmenting delivery of the agent to the biological tissue.
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16. A medical device, comprising:
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a reservoir configured to hold an agent, wherein the reservoir comprises a release port that facilitates delivery of the agent to biological tissue and an impermeable portion that is impermeable to diffusion of the agent; an injection port connected to the reservoir; a sealable base connected to the reservoir, comprising an attachment mechanism that facilitates a fluid tight seal with the biological tissue; and a pressurized system that facilitates the delivery of the agent to the biological tissue via a temporary channel created by penetration and subsequent removal of a penetrating device.
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- 19. The medical device of claim 19, wherein the temporary channel is bathed in the agent from the reservoir.
Specification