METHOD, APPARATUS, AND OPERATING SYSTEM FOR REAL-TIME MONITORING AND MANAGEMENT OF PATIENTS' HEALTH STATUS AND MEDICAL TREATMENT REGIMENS

• US 20130218588A1
• Filed: 03/15/2013
• Published: 08/22/2013
• Est. Priority Date: 03/07/1997
• Status: Abandoned Application

• Current Assignee: Madrigal Health, LLC
• Original Assignee: Madrigal Health, LLC
• Inventors: Kehr, Bruce A., Benson, Robert H., Stowell, Davin, Sohn, Evan, Starnes, James E., Maurer, David, Chapman, Dean, Farrage, David, Baumel, Irwin D., Stempler, David S.
• Application Number:
  US13/841,285
• Publication Number:
  US 20130218588A1
• Time in Patent Office: Days
• US Class Current: 705/2
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
• CPC Class Codes: A61J 2200/30 Compliance analysis for taking medication
• CPC Class Codes: A61J 2205/20 Colour codes
• CPC Class Codes: A61J 2205/30 Printed labels
• CPC Class Codes: A61J 2205/50 using icons or symbolic figures, e.g. by a graphical representation symbolising the type of pathology or the organ by an image
• CPC Class Codes: A61J 2205/70 Audible labels, e.g. for pre-recorded info or messages
• CPC Class Codes: A61J 7/0418 with electronic history memory
• CPC Class Codes: A61J 7/0481 working on a schedule basis
• CPC Class Codes: G16H 20/13 delivered from dispensers
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment

Abstract

A medical monitoring device, operating system, and method are provided for managing administration of medical treatment regimens for treating a patient'"'"'s medical conditions. The device stores information relating to administered medical treatment regimens, including medication schedule data, treatment data, patient query data, patient response data, and interactively provides information to the patient and health care providers. A method and apparatus for performing real-time monitoring of a patient'"'"'s health status using the medical monitoring device are also provided. Various aspects of the patient'"'"'s treatment regimens are modified accordingly. The medical monitoring device further analyzes monitored data in view of predefined criteria, and may promptly communicate information concerning the patient'"'"'s health status and treatment progress to remote devices that notify health care providers, and may modify the patient'"'"'s treatment regimens based on results of the analysis.

Claims

1-58. -58. (canceled)

59. A method for performing real-time monitoring of health status using a medical monitoring device capable of transmission of data to a remote device either wirelessly or via a wire, wherein the method comprises the steps of:

(a) operating the medical monitoring device in a query mode to obtain query data, wherein the query data comprises first data pertaining to treatment progress, or tracking compliance with a medication schedule, or operating the medical monitoring device in the query mode to obtain query data, wherein the query data comprises first data pertaining to treatment progress and tracking compliance with the medication schedule; and

(b) providing one or more instructions or messages, or instructions and messages, using audible signals, or visible signals, or audible signals and visible signals.

60. The method of claim 59, wherein the one or more instructions or messages comprise one or more types of signals selected from the group consisting of music, melody, sounds conveying a message, speech, symbols, and pictures.

61. The method of claim 59, wherein the query mode obtains query data using one or more types of signals selected from the group consisting of sounds conveying a message, speech, symbols, and pictures.

62. The method of claim 59, wherein the query mode, or the one or more instructions or messages are presented as a graphic image.

63. The method of claim 62, wherein the graphic images change by an algorithm within the medical monitoring device based upon adherence to a treatment regimen.

64. The method of claim 59, wherein the remote device downloads programming data into the medical monitoring device.

65. The method of claim 59, whereby the remote device transmits treatment data into the medical monitoring device either wirelessly or via wire transmission.

66. The method of claim 59, whereby the query mode may present additional queries, based upon the type of first data entered.

71. The method of claim 64, wherein said programming data or treatment data is transmitted from a database into the medical monitoring device either wirelessly or via wire transmission.

72. The method of claim 65, wherein said programming data or treatment data is transmitted from a database into the medical monitoring device either wirelessly or via wire transmission.

67. A method for performing real-time monitoring and treatment of health status using a medical monitoring device comprising:

(a) one or more networked external sensors or monitors, networked implanted sensors or monitors, or networked external and implanted sensors or monitors, to monitor health status thereby creating monitoring data,

wherein a medical monitoring device provides one or more input devices that monitor at least one physical attribute and transfers either wirelessly or via wire first data related to the monitored physical attributes to a local device medical monitoring device, or to a remote medical monitoring device, or to a local medical monitoring device and to a remote medical monitoring device.

68. The method of claim 67, wherein the medical monitoring device further comprises:

(b) an external medication delivery device, implanted medication delivery device, or external and implanted medication delivery device, to treat the health status by delivering a treatment into a body in response to monitoring data from one or more monitors.

69. The method of claim 67, wherein the treatment delivered comprises one or more types of treatments from a group consisting of pharmaceuticals, hormones, nutriceuticals, and supplements.

70. The method of claim 67, wherein the monitoring data is compared to normative data to determine whether the treatment should be delivered.

81. The method of claim 67, wherein the monitoring data comprises one or more types of data selected from the group consisting of response data provided during the query mode of the medical monitoring device, data concerning the adherence to a medical treatment regimen, data concerning physical health, data concerning physiological status, data concerning cellular functions, data concerning molecular events, and data concerning endocrine and metabolic.

82. The method of claim 67, wherein the monitoring data comprises one or more types of data selected from the group consisting of temperature data, blood pressure data, heart rate data, heart rhythm data, electrocardiographic data, breathing rate data, and intracranial pressure.

83. The method of claim 67, wherein the monitoring data is determined by assaying a bodily fluid selected from the group consisting of blood, blood serum, urine, saliva, and cerebrospinal fluid.

84. The method of claim 83, wherein the assay of the bodily fluid determines a concentration of an indicator selected from the group consisting of a steroid hormone, a polypeptide hormone, a liver enzyme, a heart protein, a muscle protein, glucose, calcium, potassium, sodium, pH, p0₂, pC0₂, ketones, an antibody, a bacterial antigen, a viral antigen, a fungal antigen, a tumor antigen, Ca⁺⁺, K⁺, and Na⁺.

85. The method of claim 67, wherein a remote device analyzes the monitoring data, transmitted either wirelessly or via wire transmission to the remote device, in accordance with an algorithm stored in the remote device, and promptly transmits either wirelessly or via wire transmission information relating to the first data or the second data to a second device via a transmission means.

73. A method for performing real-time monitoring of health status using a medical monitoring device capable of transmission of data to a remote device either wirelessly or via wire transmission, wherein the method comprises the steps of:

(a) operating the medical monitoring device in a query mode to obtain query data, wherein the query data is inputted into the medical monitoring device during the patient query mode, and wherein the query data comprises first data pertaining to treatment progress, or tracking the compliance with a medication schedule, or operating the medical monitoring device in the query mode to obtain query data, wherein the query data is inputted into the medical monitoring device during the query mode, and wherein the query data comprises first data pertaining to treatment progress and tracking the patient'"'"'s compliance with the medication schedule;

(b) promptly executing a command that requires immediate execution, wherein the command is executed by the medical monitoring device based on the query data obtained during the query mode; and

(c) storing the query data in the medical monitoring device for subsequent execution of the command when the execution command does not require immediate execution.

74. The method of claim 73, further comprising the step of:

(d) using the medical monitoring device to execute an interaction based on the first data pertaining to treatment progress, wherein the interaction generates resulting data, wherein the resulting data comprises one or more types of data selected from the group consisting of response data provided during the query mode of the medical monitoring device, data concerning the adherence to a medical treatment regimen, data concerning physical health, data concerning physiological status, data concerning cellular functions, data concerning molecular events, and data concerning endocrine and metabolic events.

75. The method of claim 74, further comprising the step of:

(e) promptly transmitting either wirelessly or via wire transmission at least a portion of the resulting data from the medical monitoring device to a remote device via transmission means when the execution command requires immediate transmission, and storing the response data in the medical monitoring device when the execution command does not require immediate transmission.

76. The method of claim 74, further comprising the step of:

(e) comparing the resulting data with target data, and, when the resulting data meets certain predefined criteria, promptly transmitting either wirelessly or via wire transmission at least a portion of the resulting data from the medical monitoring device to a remote device via the transmission means.

99. The method of claim 73, further comprising the step of:

(d) transmitting first data, or second data, or first data and second data, from the medical monitoring device either wirelessly or via wire transmission to a remote device via a transmission means.

100. The method of claim 73, wherein the medical monitoring device is operable in a medication compliance mode to display information relating to the compliance with the medication schedule, and the method further comprises the step of:

(d) displaying information relating to the compliance with the medication schedule on a display of the medical monitoring device.

101. The method of claim 73, further comprising the step of:

(d) employing a plurality of sensors to obtain second data, and transferring the second data from the plurality of sensors to the medical monitoring device.

102. The method of claim 73, further comprising the step of:

(d) comparing the resulting data with target data, and, when the resulting data meets certain predefined criteria, promptly transmitting at least a portion of the resulting data from the medical monitoring device either wirelessly or via wire transmission to a remote device via the transmission means.

77. A method for performing real-time monitoring of health status using a medical monitoring device capable of transmission of data to a remote device either wirelessly or via wire transmission, wherein the method comprises the steps of:

(a) operating the medical monitoring device in a query mode to obtain query data, wherein the query data is inputted into the medical monitoring device during the query mode, and wherein the query data comprises first data pertaining to treatment progress, or tracking the compliance with a medication schedule, or operating the medical monitoring device in the query mode to obtain query data, wherein the query data is inputted into the medical monitoring device during the query mode, and wherein the query data comprises first data pertaining to treatment progress and tracking the compliance with the medication schedule;

(b) using the medical monitoring device to execute an interaction based on the first data pertaining to treatment progress, wherein the interaction generates resulting data, and the resulting data comprises one or more types of data selected from the group consisting of response data provided during the query mode of the medical monitoring device, data concerning the adherence to a medical treatment regimen, data concerning physical health, data concerning physiological status, data concerning cellular functions, data concerning molecular events, and data concerning endocrine and metabolic events;

(c) promptly transmitting either wirelessly or via wire transmission at least a portion of the resulting data from the medical monitoring device to a remote device via a transmission means when an execution command requires immediate transmission, wherein the execution command is executed by the medical monitoring device based on the query data obtained during the query mode; and

(d) storing the resulting data in the medical monitoring device when the execution command does not require immediate transmission.

78. The method of claim 77, further comprising the step of:

(e) comparing the response data with target data, and, when the response data meets certain predefined criteria, promptly transmitting either wirelessly or via wire transmission at least a portion of the response data from the medical monitoring device to the remote device via the transmission means.

79. The method of claim 78, wherein the information retrieved from the medical monitoring device comprises one or more types of data selected from a group consisting of response data provided during a query mode of the medical monitoring device, data concerning the adherence to a medical treatment regimen, data concerning physical health, data concerning physiological status, data concerning cellular functions, data concerning molecular events, and data concerning endocrine and metabolic events.

80. A method for performing real-time monitoring of health status, using a medical monitoring device capable of communication with a remote device either wirelessly or via a wire, wherein the method comprises the steps of:

(a) operating the medical monitoring device in a query mode to obtain query data, wherein the query data is inputted into the medical monitoring device during the query mode, and wherein the query data comprises first data pertaining to treatment progress, or tracking the compliance with a medication schedule, and operating the medical monitoring device in the query mode to obtain query data, wherein the query data is inputted into the medical monitoring device during the patient query mode, and wherein the query data comprises first data pertaining to treatment progress and tracking the compliance with the medication schedule;

(b) monitoring second data relating to one or more physical attributes;

(c) analyzing the first data and the second data in accordance with a first algorithm stored in the medical monitoring device; and

(d) promptly transmitting information related to the second data, or the first data pertaining to treatment progress, or the second data and the first data, via a transmission means to the remote device either wirelessly or via wire transmission when the results of the analysis indicate that the analyzed data meets certain predefined criteria, wherein the transmitted information includes at least a portion of the first data or the second data.

86. The method of claim 80, wherein the medical monitoring device provides one or more input devices that monitor at least one of the physical attribute and transfer the second data related to the monitored physical attributes to the medical monitoring device.

87. A method for performing real-time monitoring of health status and modification of a treatment regimen, using a medical monitoring device, wherein the method comprises the steps of:

(a) operating the medical monitoring device in a query mode to obtain query data, wherein the query data is inputted into the medical monitoring device during the query mode, and wherein the query data comprises first data pertaining to treatment progress, or tracking the compliance with a medication schedule, or operating the medical monitoring device in the query mode to obtain query data, wherein the query data is inputted into the medical monitoring device during the patient query mode, and wherein the query data comprises first data pertaining to treatment progress and tracking the compliance with the medication schedule;

(b) monitoring second data relating to one or more physical attributes;

(c) analyzing the first data, or second data, or the first data and the second data, in accordance with an algorithm stored in the medical monitoring device;

(d) modifying the treatment regimen when the results of the analysis indicate that the analyzed data meets certain predefined criteria; and

(e) modifying the treatment regimen based on the first data pertaining to treatment progress.

88. A medical monitoring device capable of transmission of data either wirelessly or via wire transmission to a remote device for performing real-time monitoring of health status and administering a medical treatment regimen, wherein the medical monitoring device comprises:

(a) a memory;

(b) a display;

(c) a controller, wherein the controller operates to control access of the memory and to control display of treatment messages on the display;

(d) a receiver that receives data either wirelessly or via wire transmission from a remote device via a transmission means, wherein the receiver receives data relating to the health status and the medical treatment regimen, and the data relating to the health status and the medical treatment regimen are stored in the memory; and

(e) a plurality of keys operably connected to the controller, wherein the plurality of keys are operable to enable a query mode, wherein query data is inputted into the medical monitoring device via at least one key during the query mode, and wherein the query data comprises first data pertaining to treatment progress, wherein the medical monitoring device is operable using at least one key from the plurality of keys to track the compliance with a medication schedule and to record compliance data, wherein,

after receiving the data relating to the health status and the medical treatment regimen, the medical monitoring device promptly executes an interaction involving the medical monitoring device when an execution command requires immediate execution, wherein the execution command is executed by the medical monitoring device based on the query data obtained during the query mode, and the medical monitoring device stores the query data in the memory of the medical monitoring device for subsequent execution when the execution command does not require immediate execution.

89. The medical monitoring device of claim 88, wherein the interaction generates resulting data relating to at least one physical attribute;

and the medical monitoring device further comprises;

(f) a transmitter that transmits the resulting data either wirelessly or via wire transmission to a remote device via the transmission means, and

the medical monitoring device promptly transmits at least a portion of the resulting data either wirelessly or via wire transmission to a remote device via the transmission means when the execution command requires immediate transmission, and stores the resulting data in the memory of the medical monitoring device when the execution command does not require immediate transmission.

90. The medical monitoring device of claim 89, wherein the resulting data comprises one or more types of data selected from the group consisting of response data provided during the query mode of the medical monitoring device, data concerning the adherence to a medical treatment regimen, data concerning physical health, data concerning physiological status, data concerning cellular functions, data concerning molecular events, and data concerning endocrine and metabolic events.

91. The medical monitoring device of claim 89, wherein the resulting data comprises one or more types of data selected from the group consisting of temperature data, blood pressure data, heart rate data, heart rhythm data, electrocardiographic data, and breathing rate data.

92. The medical monitoring device of claim 89, wherein the resulting data is determined by assaying a bodily fluid selected from the group consisting of blood, blood serum, urine, and saliva.

93. The medical monitoring device of claim 92, wherein the assay of the bodily fluid determines a concentration of an indicator selected from the group consisting of a steroid hormone, a polypeptide hormone, a liver enzyme, a heart protein, a muscle protein, glucose, calcium, potassium, sodium, pH, p0₂, pC0₂, ketones, an antibody, a bacterial antigen, a viral antigen, a fungal antigen, a tumor antigen, Ca⁺⁺, K⁺, and Na⁺.

94. The medical monitoring device of claim 89, wherein the medical monitoring device compares the resulting data with target data, and, when the resulting data meets certain predefined criteria, the medical monitoring device promptly transmits at least a portion of the resulting data either wirelessly or via wire transmission to the remote device via the transmission means.

95. The medical monitoring device of claim 89, wherein the medical monitoring device analyzes the resulting data in accordance with an algorithm stored in the memory, and promptly transmits information related to the resulting data either wirelessly or via wire transmission to a remote device via the transmission means when the results of the analysis indicate that the resulting data meets certain predefined criteria, wherein the transmitted information includes at least a portion of the resulting data.

96. The medical monitoring device of claim 89, wherein the medical monitoring device interfaces with one or more input devices that monitor at least one physical attribute and transfers the resulting data to the medical monitoring device.

97. A medical monitoring device for performing real-time monitoring of health status and modification of a treatment regimen, wherein the medical monitoring device comprises:

(a) a memory;

(b) a display;

(c) a controller, wherein the controller operates to control access of the memory and to control display of treatment messages on the display; and

(d) a plurality of keys operably connected to the controller, wherein the plurality of keys are operable to enable a query mode to obtain query data, wherein the query data is inputted into the medical monitoring device via at least one key during the query mode, and wherein the query data comprises first data pertaining to treatment progress, wherein the medical monitoring device is operable using at least one of the plurality of keys to track the compliance with a medication schedule and to record compliance data, wherein the medical monitoring device operates to monitor second data relating to one or more physical attributes, and to analyze the first data, or second data, or first data and second data, in accordance with an algorithm stored in the memory of the medical monitoring device, and to modify the treatment regimen when the results of the analysis indicate that the first data, or the second data, or the first data and the second data, meets certain predefined criteria, and to modify the treatment regimen based on the first data pertaining to treatment progress.

98. A medical monitoring device capable of transmission of data either wirelessly or via wire transmission to a remote device for performing real-time monitoring of health status and administering a medical treatment regimen, wherein the medical monitoring device comprises:

(a) a memory;

(b) a display;

(c) a controller, wherein the controller operates to control access of the memory and to control display of treatment messages on the display; and

(d) a transmitter that transmits first data either wirelessly or via a wire to a remote device via a transmission means; and

(e) a plurality of keys operably connected to the controller, wherein the plurality of keys are operable to enable a query mode to obtain query data, wherein the query data is inputted into the medical monitoring device via at least one of the plurality of keys during the query mode, and wherein the query data comprises data pertaining to treatment progress, wherein the medical monitoring device is operable using at least one of the plurality of keys to track the compliance with a medication schedule and to record compliance data,

wherein the remote device receives first information relating to the health status and second information relating to the adherence to the medical treatment regimen by polling the medical monitoring device and receiving the first information and the second information either wirelessly or via the wire via the transmission means.

103. A method for performing real-time monitoring of a health status using a medical monitoring device capable of transmission of data to a remote device either wirelessly or via a wire, wherein the method comprises the steps of:

(a) monitoring health via one or more external sensors or monitors, implanted sensors or monitors, or external and implanted sensors or monitors, so as to create monitoring data;

(b) operating the medical monitoring device in a query mode to obtain query data, wherein the query data is inputted into the medical monitoring device during the query mode, and wherein the query data comprises first data pertaining to treatment progress, or tracking the compliance with a medication schedule, or operating the medical monitoring device in the query mode to obtain query data, wherein the query data is inputted into the medical monitoring device during the query mode, and wherein the query data comprises first data pertaining to treatment progress and tracking the compliance with the medication schedule;

(c) analyzing the first data, or the monitoring data, or the first data and the monitoring data, in accordance with an algorithm stored in the medical monitoring device or in a second device; and

(d) modifying the treatment regimen when the results of the analysis indicate that the first data, the monitoring data, or the first data and the monitoring data, meet certain predefined criteria.

104. The method of claim 103, wherein the one or more external sensors or monitors, implanted sensors or monitors, or external and implanted sensors or monitors comprise a plurality of sensors that obtain second data, and the plurality of sensors transfer the second data to the medical monitoring device either wirelessly or via wire transmission, the monitoring data is created from the second data.

105. The method of claim 104, wherein the plurality of sensors persistently monitor health or are actively polled for the second data so as to create the monitoring data.

106. The method of claim 104, wherein the second data is selected from the group consisting of one or more of physiological data, cellular data, molecular data, endocrine data, and metabolic data.

107. The method of claim 103, wherein the query data is configured as a survey.

108. The method according to claim 103, further comprising the step(s) of:

(e) analyzing the first data, or the monitoring data, or the first data and the monitoring data, in accordance with another algorithm stored in the second device, wherein the second device communicates with the medical monitoring device, and wherein the second device analyzes the first data, or the monitoring data, or the first data and the monitoring data, and downloads a modified treatment regimen to the medical monitoring device.

109. The method according to claim 103, further comprising the step(s) of:

(e) analyzing the first data, or the monitoring data, or the first data and the monitoring data, in accordance with another algorithm stored in a local medical monitoring device, or in a remote medical monitoring device, or in the local medical monitoring device and in the remote medical monitoring device, to triage the severity of an event detected by sensors of the medical monitoring device and thereby direct an appropriate level and type of medical care.

110. The method according to claim 103, further comprising the step(s) of:

(e) analyzing the first data, or the monitoring data, or the first data and the monitoring data, in accordance with another algorithm stored in a local medical monitoring device, or in a remote medical monitoring device, or in the local medical monitoring device and in the remote medical monitoring device, to triage the severity of an event detected by sensors of the medical monitoring device and thereby direct an appropriate level and type of medical care.

111. The method according to claim 103, further comprising the step(s) of:

(e) analyzing the first data, or the monitoring data, or the first data and the monitoring data, in accordance with another algorithm stored in a local medical monitoring device, or in a remote medical monitoring device, or in the local medical monitoring device and in the remote medical monitoring device, to triage the severity of an event detected by sensors of the medical monitoring device and thereby notify one or more appropriate medical care providers.

112. The method according to claim 103, further comprising the step(s) of:

(e) analyzing the first data, or the monitoring data, or the first data and the monitoring data, in accordance with the algorithm stored in the second device, wherein the second device comprises a local medical monitoring device, or a remote medical monitoring device, or both the local medical monitoring device and the remote medical monitoring device, to triage and to select data detected by the sensors of the medical monitor and to transmit data along with instructions specific to a medical provider'"'"'s tasks, or to a medical care support provider'"'"'s tasks, or to both the medical care provider'"'"'s tasks and to the medical care support provider'"'"'s tasks.

113. The method according to claim 103, further comprising the step(s) of:

(e) analyzing the first data, or the monitoring data, or the first data and the monitoring data, in accordance with another algorithm stored in a local medical monitoring device, or in a remote medical monitoring device, or in the local medical monitoring device and in the remote medical monitoring device, to calculate patient health risk associated with the event detected by the sensors of the medical monitoring device and, thereby, direct modulation of a medical treatment regimen, or actuation of a medical delivery device, or both the modulation of the medical treatment regimen and the actuation of the medical delivery device.

114. The method of claim 103, wherein during the query mode, activation of an “

I Can'"'"'t”

response signals a microcontroller to display an appropriate message.

115. The method of claim 103, wherein the query data is inputted into the medical monitoring device during the query mode via a query interface.

116. The method of claim 115, wherein the query interface comprises one or more soft keys or one or more touch points or a combination of at least one soft key and at least one touch point.

117. The method of claim 103, wherein the steps (c) and (d) occur contemporaneously with steps (a) and (b) so that modification of the treatment regimen occurs in real time and contemporaneously with the creation of monitoring data and with the input of query data into the medical monitoring device during the query mode.

118. The medical monitoring device of claim 103, wherein the resulting data comprises one or more types of data selected from the group consisting of response data provided during the query mode of the medical monitoring device, data concerning the adherence to a medical treatment regimen, data concerning physical health, data concerning physiological status, data concerning cellular functions, data concerning molecular events, and data concerning endocrine and metabolic events.

119. The medical monitoring device of claim 103, wherein the resulting data comprises one or more types of data selected from the group consisting of temperature data, blood pressure data, heart rate data, heart rhythm data, electrocardiographic data, breathing rate data, and intracranial pressure data.

120. The medical monitoring device of claim 103, wherein the resulting data is determined by assaying a bodily fluid selected from the group consisting of blood, blood serum, urine, saliva, and cerebrospinal fluid.

121. The medical monitoring device of claim 103, wherein the assay of the bodily fluid determines a concentration of an indicator selected from the group consisting of a steroid hormone, a polypeptide hormone, a liver enzyme, a heart protein, a muscle protein, glucose, calcium, potassium, sodium, pH, p0₂, pC0₂, ketones, an antibody, a bacterial antigen, a viral antigen, a fungal antigen, a tumor antigen, Ca⁺⁺, K⁺, and Na⁺.

122. The method of claim 103, further comprising the step of:

(e) analyzing the first data, or the monitoring data, or the first data and the monitoring data, in accordance with another algorithm stored in a local medical monitoring device, or in a remote medical monitoring device, or in the local medical monitoring device and in the remote medical monitoring device, to triage the severity of an event detected by sensors of the medical monitoring device and thereby notify one or more persons in the proximity of the patient.

123. A medical monitoring device capable of transmission of data either wirelessly or via wire transmission to a remote device for performing real-time monitoring of health status and administering a medical treatment regimen, wherein the medical monitoring device comprises:

(a) a memory;

(b) a display;

(c) a controller, wherein the controller operates to control access of the memory and to control display of treatment messages on the display;

(d) a receiver that receives data either wirelessly or via wire transmission from a remote device via a transmission means, wherein the receiver receives data relating to the health status and the medical treatment regimen, and the data relating to the health status and the medical treatment regimen are stored in the memory; and

(e) a plurality of keys operably connected to the controller, wherein one or more of the plurality of keys are operable to obtain information related to one or medications, or one or more diseases, or one or medications and one or more diseases.

124. A medical monitoring device capable of transmission of data either wirelessly or via wire transmission to a remote device for performing real-time monitoring of health status and administering a medical treatment regimen, wherein the medical monitoring device comprises:

(a) a memory;

(b) a display;

(c) a controller, wherein the controller operates to control access of the memory and to control display of treatment messages on the display;

(d) a receiver that receives data either wirelessly or via wire transmission from a remote device via a transmission means, wherein the receiver receives data relating to the health status and the medical treatment regimen, and the data relating to the health status and the medical treatment regimen are stored in the memory; and

(e) a plurality of keys operably connected to the controller, wherein one or more of the plurality of keys are operable to obtain information related to why the patient is not taking his or her medication.