POLYMERIC VDAT NANOPARTICLES FOR USE IN BIOSENSORS
First Claim
1. A biosensor comprising:
- a substrate;
at least one electrode disposed on the substrate; and
a uric acid scavenger layer containing polymeric nanoparticles including polymerized vinyl-4,6-diamino-1,3,5-triazine (polyVDAT nanoparticles) disposed above the at least one electrode.
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Accused Products
Abstract
A biosensor (such as an electrochemical-based analytical test strip configured for the determination of glucose in a whole blood sample) includes a substrate, an electrode disposed on the substrate and a uric acid scavenger layer containing polymeric vinyl-4,6-diamino-1,3,5-triazine (polyVDAT) nanoparticles. Aqueous compositions useful in, for example, the manufacturing of such biosensors include polyVDAT nanoparticles and water with the polyVDAT nanoparticles being present as a dispersion in the water. A method for determining an analyte in a bodily fluid sample containing uric acid includes applying a bodily fluid sample containing uric acid to a biosensor such that the bodily fluid sample comes into contact with a uric acid scavenger layer containing polymeric vinyl-4,6-diamino-1,3,5-triazine (polyVDAT) nanoparticles and determining the analyte based on an electronic signal produced by the biosensor.
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Citations
36 Claims
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1. A biosensor comprising:
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a substrate; at least one electrode disposed on the substrate; and a uric acid scavenger layer containing polymeric nanoparticles including polymerized vinyl-4,6-diamino-1,3,5-triazine (polyVDAT nanoparticles) disposed above the at least one electrode. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. An aqueous vinyl-4,6-diamino-1,3,5-triazine (VDAT) composition for use in analytical test strips, the aqueous vinyl-4,6-diamino-1,3,5-triazine (VDAT) composition comprising:
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polymeric nanoparticles including polymerized vinyl-4,6-diamino-1,3,5-triazine (polyVDAT nanoparticles); and water, wherein the polyVDAT nanoparticles are present as a dispersion in the water. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25)
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26. A method for determining an analyte in a bodily fluid sample containing uric acid, the method comprising:
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applying a bodily fluid sample containing uric acid to a biosensor such that the bodily fluid sample comes into contact with a uric acid scavenger layer containing polymeric nanoparticles that include polymerized vinyl-4,6-diamino-1,3,5-triazine (polyVDAT nanoparticles); and determining the analyte based on an electronic signal produced by the biosensor. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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Specification