CORRECTION METHOD OF FLUORESCENCE SENSOR AND FLUORESCENCE SENSOR
First Claim
1. A correction method of a fluorescence sensor comprising:
- a first detection signal acquiring step for acquiring, at a first temperature, a first detection signal using a fluorescence sensor including a light-emitting element configured to generate excitation light, an indicator layer configured to generate fluorescent light corresponding to the excitation light and an analyte amount, and a photoelectric conversion element configured to output a detection signal in which an excitation light detection signal due to the excitation light is superimposed on a fluorescent light detection signal due to the fluorescent light, the fluorescence sensor having a temperature detecting function for outputting a temperature detection signal and a temperature adjusting function;
a second detection signal acquiring step for acquiring, at a second temperature, a second detection signal when the analyte amount is the same as the analyte amount in the first detection signal acquiring step;
a correction coefficient calculating step for calculating, on the basis of the first detection signal and the second detection signal, a correction coefficient for correcting the fluorescent light detection signal; and
a correcting step for correcting subsequent detection signals using the correction coefficient and the temperature detection signal.
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Abstract
A correction method of a fluorescence sensor includes a first detection signal acquiring step for acquiring, at a first temperature, a first detection signal using a fluorescence sensor having a temperature detecting function and a temperature adjusting function, a second detection signal acquiring step for acquiring, at a second temperature, a second detection signal when an analyte amount is the same as an analyte amount in the first detection signal acquiring step, a correction coefficient calculating step for calculating, on the basis of the first detection signal and the second detection signal, a correction coefficient for correcting the fluorescent light detection signal, and a correcting step for correcting subsequent detection signals using the correction coefficient and a temperature detection signal.
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Citations
12 Claims
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1. A correction method of a fluorescence sensor comprising:
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a first detection signal acquiring step for acquiring, at a first temperature, a first detection signal using a fluorescence sensor including a light-emitting element configured to generate excitation light, an indicator layer configured to generate fluorescent light corresponding to the excitation light and an analyte amount, and a photoelectric conversion element configured to output a detection signal in which an excitation light detection signal due to the excitation light is superimposed on a fluorescent light detection signal due to the fluorescent light, the fluorescence sensor having a temperature detecting function for outputting a temperature detection signal and a temperature adjusting function; a second detection signal acquiring step for acquiring, at a second temperature, a second detection signal when the analyte amount is the same as the analyte amount in the first detection signal acquiring step; a correction coefficient calculating step for calculating, on the basis of the first detection signal and the second detection signal, a correction coefficient for correcting the fluorescent light detection signal; and a correcting step for correcting subsequent detection signals using the correction coefficient and the temperature detection signal. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A fluorescence sensor comprising:
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a light-emitting element configured to generate excitation light; an indicator layer configured to generate fluorescent light corresponding to the excitation light and an analyte amount; and a photoelectric conversion element configured to output a detection signal in which an excitation light detection signal due to the excitation light is superimposed on a fluorescent light detection signal due to the fluorescent light, wherein the fluorescence sensor has a temperature detecting function for outputting a temperature detection signal and a temperature adjusting function. - View Dependent Claims (9, 10, 11, 12)
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Specification