Methods, Devices, Systems and Compositions for Detecting Gases

• US 20130236980A1
• Filed: 09/10/2012
• Published: 09/12/2013
• Est. Priority Date: 03/12/2012
• Status: Abandoned Application

• Current Assignee: Respirion, LLC
• Original Assignee: Respirion, LLC
• Inventors: Moretti, Eugene W., Wood, Robert Lavin, Shang, Allan Bruce
• Application Number:
  US13/609,024
• Publication Number:
  US 20130236980A1
• Time in Patent Office: Days
• US Class Current: 436/133
• CPC Class Codes: A61B 5/0836 Measuring rate of CO2 production
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: G01J 1/50 using change in colour of an indicator, e.g. actinometer
• CPC Class Codes: G01N 21/783 for analysing gases
• CPC Class Codes: Y10T 436/204998 Inorganic carbon compounds

Abstract

A method of monitoring a respiratory stream can be provided by monitoring color change of a color change material to determine a CO2 level of the respiratory stream in contact with the color change material by emitting visible light onto the color change material. Related devices, systems, and compositions are also disclosed.

Claims

1-15. -15. (canceled)

16. A device comprising:

a visible light emitter circuit configured to provide emitted visible light into a breathing circuit;

a first visible light sensor circuit configured to receive a first portion of the emitted visible light; and

a processor circuit, coupled to the visible light emitter circuit and to the first visible light sensor circuit, the processor circuit configured to determine a CO2 level of a respiratory stream in the breathing circuit based on the first portion of the emitted visible light.

17. The device of claim 16 wherein the first visible light sensor circuit is configured to provide a reactive signal to the processor circuit as a color indication of the CO2 level based on the first portion of the emitted visible light.

18. The device of claim 16 wherein the visible light emitter circuit is located on a first side of the breathing circuit and the first visible light sensor circuit is located on a second side of the breathing circuit, opposite the first side.

19. The device of claim 16 wherein the visible light emitter circuit and the first visible light sensor circuit is located on a first side of the breathing circuit, the device further comprising:

a reflector on a second side of the breathing circuit, opposite the first side, positioned to reflect the emitted visible light from the visible light emitter circuit to the first visible light sensor circuit.

20. The device of claim 16 further comprising:

a color change material inside the breathing circuit overlying the first visible light sensor circuit, wherein the emitted visible light impinges a first surface of the color change material and the first portion of the emitted visible light exits a second surface of the color change material to impinge the first visible light sensor circuit.

21. The device of claim 16 wherein the processor circuit is configured to determine the CO2 level based on a comparison of at least two color components of the first portion of the emitted visible light.

22. The device of claim 21 wherein the at least two color components comprise red and green or red and blue.

23. The device of claim 20 wherein the visible light emitter circuit and the first visible light sensor circuit is remote from the respiratory stream, the device further comprising:

an optical transmission medium extending from the color change material to the visible light emitter circuit and to the first visible light sensor circuit.

24. The device of claim 16 wherein the breathing circuit comprises a conduit in which at least a portion of the respiratory stream is enclosed.

25. The device of claim 24 wherein the conduit is open to an ambient environment outside the respiratory stream.

26. The device of claim 16 wherein the breathing circuit comprises a conduit configured for direct coupling to an airway of a subject for which the CO2 level is determined.

27. The device of claim 24 wherein the processor circuit is configured to communicate the CO2 level to an electronic device that is remote from the device.

28. The device of claim 27 wherein the electronic device comprises a smartphone, tablet, or PDA.

29. A device comprising:

a visible light emitter circuit configured to provide emitted visible light into a respiratory stream;

a first visible light sensor circuit configured to receive a first portion of the emitted visible light; and

a processor circuit, coupled to the visible light emitter circuit and to the first visible light sensor circuit, the processor circuit configured to determine a CO2 level in the respiratory stream based on the first portion of the emitted visible light.

30. The device of claim 29 wherein the respiratory stream is unenclosed by a breathing circuit adapter.

31. The device of claim 29 further comprising:

a member configured for mounting of at least the first visible light sensor circuit thereon and configured for positioning within the respiratory stream.

32. The device of claim 31 wherein the member comprises an adjustable elongated member having a distal portion, outside the respiratory stream, configured for attachment to a subject for which the CO2 level is to be determined and a proximate portion for mounting the at least first visible light sensor circuit.

33. A composition for use in monitoring a respiratory stream comprising:

a color change material configured to change from a first color to a second color in response to an increase in CO₂ within the respiratory stream, where the first color includes more of a first component than a second component or more than a third component and the second color includes less of the first component than the second component or less than the third component.

34. A method of determining a CO₂ level of a respiratory stream, the method comprising:

electronically emitting visible light into the respiratory stream to provide emitted visible light onto at least a portion of a color change material in contact with the respiratory stream;

electronically sensing a first color generated by a reactive portion of color change material responsive to the emitted visible light; and

determining the CO2 level of the respiratory stream based on the first color.

35. The method of claim 34 wherein electronically sensing a first color comprises electronically sensing a first portion of the emitted visible light passing through the reactive portion of color change material as an indication of the first color, the method further comprising:

providing a reactive signal to a processor circuit as indication of the CO2 level based on the first portion of the emitting visible light.

36. The method of claim 35 wherein determining the CO2 level of the respiratory stream further comprises:

determining first color components of the first color; and

determining a first color ratio of the first color components to one another.

37. The method of claim 35 further comprising:

determining first color components of the first color;

determining a first color ratio of the first color components to one another; and

determining a respiration rate associated with the respiratory stream based on periodic determination of the first color ratio to provide a data set associated with at least one complete respiration cycle of the respiratory stream.

38. The method of claim 37 wherein determining the CO2 level of the respiratory stream further comprises:

determining the CO2 level based on a directly adjacent peak to peak values among the first color ratios in the data set and/or based on a minimum value of first color ratios in the data set.

39. The method of claim 38 wherein determining the CO2 level based on a directly adjacent peak to peak values among the first color ratios in the data set and/or based on a minimum value of first color ratios in the data set comprises:

determining the CO2 level based more on the directly adjacent peak to peak values than on the minimum value responsive to a first respiration rate; and

determining the CO2 level based more on the minimum value than on the directly adjacent peak to peak values responsive to a second respiration rate that is greater than the first respiration rate.