SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA

• US 20130237786A1
• Filed: 04/23/2013
• Published: 09/12/2013
• Est. Priority Date: 08/01/2003
• Status: Abandoned Application

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Goode, Paul V. Jr., Brauker, James H., Kamath, Apurv Ullas, Carr-Brendel, Victoria E.
• Application Number:
  US13/868,766
• Publication Number:
  US 20130237786A1
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes

Abstract

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

Claims

1. A method for initializing a glucose sensor, comprising:

analyzing, with an electronic device, a glucose related signal from a glucose sensor to determine a sensor stability, wherein at least a portion of the glucose sensor is beneath a skin surface of a host; and

reporting glucose related information when the sensor is determined to be stable, wherein the glucose related information is not reported prior to determining that the sensor is stable.

2. The method of claim 1, wherein sensor stability is determined using reference data.

3. The method of claim 2, wherein the reference data is obtained by sampling blood of the individual.

4. The method of claim 2, wherein the reference data is obtained from a glucose test strip.

5. The method of claim 1, further comprising analyzing the sensor signal to determine whether a sensor sensitivity variability exists that exceeds a predetermined threshold, over a predetermined time period.

6. The method of claim 1, wherein reporting glucose related information is performed after about one hour following the insertion of the sensor.