APPARATUSES FOR SECURING COMPONENTS OF A DRUG DELIVERY SYSTEM DURING TRANSPORT AND METHODS OF USING SAME

• US 20130245596A1
• Filed: 04/30/2013
• Published: 09/19/2013
• Est. Priority Date: 10/02/2007
• Status: Active Grant

• Current Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Original Assignee: Medimop Medical Projects Ltd. (West Pharmaceutical Services Incorporated)
• Inventors: CABIRI, Oz, FILMAN, Reuven Y., BAR-EL, Yossi
• Granted Patent: US 9,656,019 B2
• Time in Patent Office: Days
• US Class Current: 604/500
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 2005/1426 with means for preventing access to the needle after use
• CPC Class Codes: A61M 2005/14268 with a reusable and a disposable component
• CPC Class Codes: A61M 2005/31518 designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
• CPC Class Codes: A61M 2205/3523 using telemetric means
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: Y10T 29/49826 Assembling or joining

Abstract

An assembly of a drug delivery system, comprising: a first component; a second component which is configured to move linearly with respect to the first component; and, a resistance element configured to resist linear movement during transport of the first component with respect to the second component in a closed transport configuration but which is adapted to be overcome during nominal operation of the drug delivery system.

Claims

1. An assembly of a drug delivery system, comprising:

a first component;

a second component which is configured to move linearly with respect to the first component; and

,

a resistance element configured to resist linear movement during transport of the first component with respect to the second component in a closed transport configuration but which is adapted to be overcome during nominal operation of the drug delivery system.

2. An assembly of claim 1, wherein the closed transport configuration is the state of the assembly before the linear movement of the second component with respect to the first component effectuates pumping in the drug delivery system.

3. An assembly of claim 1, wherein the first component includes a pushing element and the second component includes a drive element.

4. An assembly of claim 1, wherein the resistance element includes an annular ring and a counterpart lip.

5. An assembly of claim 4, wherein a pushing element is provided with the annular ring and a drive element is provided with the counterpart lip, which when the ring and the lip are forced together create the resistance to extension of the assembly.

6. An assembly of claim 1, wherein the first component and the second component are linked by a screw thread and linear movement is achieved by rotation of at least one of the first component and the second component.

7. An assembly of claim 6, wherein a portion of said screw thread is configured with increased friction in relation to the other portions of the screw thread.

8. An assembly, of claim 7, wherein said portion is provided with increased friction by making a gap between a thread and the next thread tighter.

9. An assembly of claim 7, wherein said portion is provided with increased friction by making a thread less deep than the other threads of the internal screw.

10. An assembly of claim 7, wherein said portion is provided with increased friction by altering the shape a screw to increase friction between threads as it turns.

11. An assembly of claim 7, wherein said portion is provided with increased friction by coating a thread with at least one of an abrasive material and an adhesive material.

12. An assembly of claim 1, wherein the resistance element includes multiple interference elements.

13. An assembly of claim 12, where said each resistance element includes a tooth fitting into a recess.

14. An assembly of claim 1, wherein the torque required to overcome the resistance element less than the nominal operative torque required to stall a driving motor of the drug delivery system.

15. An assembly of claim 1, wherein the required torque to overcome the resistance element is varied from 50-300 gr-cm.

16. An assembly of claim 1, wherein the resistance element is overcome by deformation of at least a portion of at least one of the first and second components.

17. An assembly of claim 16, wherein the deformation is at least one of elastic and plastic deformation.

18. An assembly of claim 1, wherein the resistance element includes a sloped contact surface.

19. A method of using an assembly of a drug delivery system, comprising:

providing resistance to linear extension of the assembly when the assembly is in a closed transport configuration;

placing the closed assembly into the drug delivery system;

activating the drug delivery system;

applying torque to overcome the provided resistance; and

,

extending the assembly to exert pressure on a fluid in a cartridge of the drug delivery system.

20. A method according to claim 19, further comprising closing the assembly prior to the placing.

21. A method according to claim 19, wherein providing resistance comprises abutting an annular ring of a pushing element of the assembly with a lip of a drive element of the assembly to distribute the resistance over a large area

22. A method according to claim 19, wherein providing resistance is distributed over a plurality of separate portions of an annular ring.

23. A method according to claim 19, wherein providing resistance comprises heightening the friction against turning for at least one of a first few threads of an internal screw of the assembly.

24. A method according to claim 23, wherein heightening the friction comprises at least one of narrowing the gap between threads, making the threads less deep and shaping the internal screw irregularly.

25. A method according to claim 23, wherein heightening the friction comprises coating the at least one thread with at least one of an abrasive material and an adhesive material.

26. A method of transporting an assembly of a drug delivery system, comprising:

manufacturing the assembly to include at least one resistance element adapted to resist vibrations which cause unintentional linear extension of the assembly but which is overcome by a required torque during nominal operation of the drug delivery system;

configuring the assembly for transport; and

,

transporting the assembly.

27. A method according to claim 26, wherein the required torque to overcome the resistance element is at least 50 gr-cm.

28. A method according to claim 26, wherein the required torque to overcome the resistance element is at least 100 gr-cm.