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Method and System for Non-Invasive Functional Assessment of Coronary Artery Stenosis

  • US 20130246034A1
  • Filed: 03/11/2013
  • Published: 09/19/2013
  • Est. Priority Date: 03/13/2012
  • Status: Active Grant
First Claim
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1. A method for non-invasive assessment of coronary artery stenosis, comprising:

  • extracting patient-specific anatomical measurements of the coronary arteries from medical image data of a patient acquired during rest state;

    calculating patient-specific rest state boundary conditions of a model of coronary circulation representing the coronary arteries based on the patient-specific anatomical measurements and non-invasive clinical measurements of the patient at rest;

    calculating patient-specific hyperemic boundary conditions of the model of coronary circulation based on the rest boundary conditions and a model for simulated hyperemia;

    simulating hyperemic blood flow and pressure across at least one stenosis region of at least one coronary artery using the model of coronary circulation and the patient-specific hyperemic boundary conditions; and

    calculating fractional flow reserve (FFR) of the at least one stenosis region based on the simulated hyperemic blood flow and pressure.

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