OCCLUSIVE DEVICES AND METHODS OF USE

• US 20130253572A1
• Filed: 03/15/2013
• Published: 09/26/2013
• Est. Priority Date: 03/23/2012
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: LOSORDO, Michael Louis, MOLAEI, Masoud, NAGESWARAN, Ashok, GRIFFIN, Stephen, DAVIDSON, Jim
• Granted Patent: US 9,687,245 B2
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device

Abstract

An aneurysm therapy system, can include a catheter and an occlusive device. The catheter can have a proximal end, a distal end, and a lumen extending between the proximal and distal ends. The proximal end can include a self-expanding distal section, and the distal section can comprise a coil portion. The occlusive device can be disposed within the lumen and configured to reside in the aneurysm to restrict fluid flow within the aneurysm.

Claims

1. An aneurysm therapy system, comprising, in combination:

a catheter having a proximal end, a distal end, and a lumen extending between the proximal and distal ends; and

an occlusive device, disposed within the lumen and configured to reside in the aneurysm to restrict fluid flow within the aneurysm, the device comprising;

a distal section comprising a coil having an outer diameter, a coil length, and a coil flexibility; and

a self-expanding braided proximal section having (i) a radially compressed state with a first diameter when positioned within the delivery lumen and (ii) a radially expanded state with a second diameter, greater than the coil diameter, when unconstrained, (iii) a braid length greater than the coil length, and (iv) a braid flexibility less than the coil flexibility per unit length;

wherein the proximal section is configured to expand during advancement out of the distal end of the catheter, and the distal section is configured to distribute, along at least a portion of the coil length, a force of the advancement along an aneurysm interior wall.

2. The system of claim 1, wherein the coil outer diameter is substantially constant.

3. The system of claim 1, wherein the distal section is configured to abut the aneurysm interior wall to direct the distalmost proximal section as the proximal section is advanced into the aneurysm.

4. The system of claim 1, wherein the first diameter is substantially the same as the coil diameter when the proximal section is in the delivery lumen.

5. The system of claim 1, wherein the distal section comprises a curved distal end.

6. The system of claim 5, wherein a maximum radius of curvature of the distal section is less than a maximum radius of curvature of the proximal section.

7. The system of claim 1, wherein the proximal section has a secondary preset, three-dimensional shape when in the radially expanded state.

8. The system of claim 1, wherein the braid length is from about 50 mm to about 150 mm.

9. The system of claim 1, wherein the coil length is from about 30 mm to about 40 mm.

10. The system of claim 1, wherein the second diameter is from about 2.8 to about 5.8 times the first diameter, and the first diameter is from about 0.017 inches and about 0.021 inches.

11. The system of claim 1, wherein the proximal section comprises a first bend within a first plane and a second bend out of the first plane.

12. The system of claim 1, wherein a wall of the proximal section comprises pores having an average pore size from about 25 microns to about 250 microns.

13. The system of claim 1, further comprising a shaping member extending within the proximal section and coupled to the proximal section.

14. The system of claim 1, further comprising a transition section, between the proximal and distal sections, having a lower flexibility per unit length than the coil flexibility and the braid flexibility.

15. A method of treating an aneurysm, the method comprising:

positioning a catheter, within a vessel, adjacent the aneurysm;

advancing, from a distal end of the catheter, a distal section of an occlusive device, the distal section comprising a coil having a coil length and a coil diameter;

expanding a proximal section of the device from a radially compressed state with a first diameter when positioned within the delivery lumen to a radially expanded state with a second diameter, greater than the coil diameter, when unconstrained by advancing the proximal section out of the distal end of the catheter;

wherein as the proximal section is advanced out of the distal end of the catheter, the distal section distributes, along at least a portion of the coil length, a force of the advancing along an aneurysm interior wall.

16. The method of claim 15, wherein the proximal section comprises a flexibility that is greater than a distal section flexibility per unit length.

17. The method of claim 15, wherein advancing the distal section comprises abutting the aneurysm interior wall with a sidewall of the coil.

18. The method of claim 15, further comprising advancing an additional occlusive device into the aneurysm.

19. The method of claim 18, wherein the additional occlusive device comprises at least one of a non-expanding coil or a braided device.

20. The method of claim 18, wherein the additional occlusive device comprises a diameter less than the proximal section diameter.

21. The method of claim 18, wherein the proximal section is positioned within the aneurysm such that a segment of the proximal section extends across an ostium of the aneurysm to inhibit egress of the additional device.

22. An occlusive device comprising:

a distal section comprising a coil having an outer cross-sectional dimension, a coil length, and a coil flexibility;

a self-expanding braided proximal section having (i) a radially compressed state with a first cross-sectional dimension when positioned within the delivery lumen and (ii) a radially expanded state with a second cross-sectional dimension, greater than the coil cross-sectional dimension, when unconstrained, (iii) a braid length greater than the coil length, and (iv) a braid flexibility less than the coil flexibility per unit length; and

a transition section, between the proximal and distal sections, having a lower flexibility per unit length than the coil flexibility and the braid flexibility;

wherein the device is configured to reside in an aneurysm to restrict fluid flow within the aneurysm.

23. The device of claim 22, wherein the braid length is from about 50 mm to about 150 mm.

24. The device of claim 22, wherein the coil length is from about 30 mm to about 40 mm.