COLLAPSIBLE VALVE PROSTHESIS
First Claim
1. A collapsible valve prosthesis including an armature and a set of prosthetic valve leaflets supported by the armature, the armature expandable from a contracted condition to an expanded condition for anchoring at an annulus of a natural valve site, wherein the armature includes:
- a tubular intra-annular portion including a frame and defining a blood flow lumen having an inflow side and an outflow side, the tubular intra-annular portion supporting the set of prosthetic valve leaflets in the blood flow lumen, the set of prosthetic valve leaflets substantially enabling free flow of fluid through the valve prosthesis from the inflow side to the outflow side and substantially preventing free flow of fluid through the valve prosthesis from the outflow side to the inflow side, the set of prosthetic valve leaflets being provided with outward formations for coupling with the natural valve site, andat least one extra-annular portion including a frame and linked to the intra-annular portion, the intra-annular portion and the at least one extra-annular portion being structurally separate components, the at least one extra-annular portion including an over-annular portion to extend collar-like over the annulus of the natural valve site at the inflow side of the blood flow lumen.
2 Assignments
0 Petitions
Accused Products
Abstract
A collapsible valve prosthesis includes an armature and a set of prosthetic valve leaflets supported by the armature. The armature is expandable from a contracted condition to an expanded condition for anchoring at an annulus of a natural valve site, and includes a tubular intra-annular portion defining a blood flow lumen having an inflow side and an outflow side. The tubular intra-annular portion supports the prosthetic valve leaflets in the blood flow lumen and is provided with outward formations for coupling with the natural valve site. The armature includes an over-annular portion linked to the intra-annular portion to extend collar-like over the annulus of the natural valve site at the inflow side of the blood flow lumen. The armature may also include an under-annular portion to extend collar-like at the outflow side of the blood flow lumen. The prosthesis may permit mitral valve replacement (MVR) without removing the native valve leaflets and the chordae tendineae.
146 Citations
21 Claims
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1. A collapsible valve prosthesis including an armature and a set of prosthetic valve leaflets supported by the armature, the armature expandable from a contracted condition to an expanded condition for anchoring at an annulus of a natural valve site, wherein the armature includes:
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a tubular intra-annular portion including a frame and defining a blood flow lumen having an inflow side and an outflow side, the tubular intra-annular portion supporting the set of prosthetic valve leaflets in the blood flow lumen, the set of prosthetic valve leaflets substantially enabling free flow of fluid through the valve prosthesis from the inflow side to the outflow side and substantially preventing free flow of fluid through the valve prosthesis from the outflow side to the inflow side, the set of prosthetic valve leaflets being provided with outward formations for coupling with the natural valve site, and at least one extra-annular portion including a frame and linked to the intra-annular portion, the intra-annular portion and the at least one extra-annular portion being structurally separate components, the at least one extra-annular portion including an over-annular portion to extend collar-like over the annulus of the natural valve site at the inflow side of the blood flow lumen. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A collapsible valve prosthesis including an armature and a set of prosthetic valve leaflets supported by the armature, the armature expandable from a contracted condition to an expanded condition for anchoring at an annulus of a natural valve site, wherein the armature includes:
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a sheath, the sheath at least partially covering the armature, a tubular balloon-expandable intra-annular portion including a frame and defining a blood flow lumen having an inflow side and an outflow side, the tubular intra-annular portion supporting the set of prosthetic valve leaflets in the blood flow lumen, the set of prosthetic valve leaflets substantially enabling free flow of fluid through the valve prosthesis from the inflow side to the outflow side and substantially preventing free flow of fluid through the valve prosthesis from the outflow side to the inflow side, the set of prosthetic valve leaflets being provided with outward formations for coupling with the natural valve site, and at least one self-expandable extra-annular portion including a frame and linked to the intra-annular portion, the intra-annular portion and the at least one extra-annular portion being separate pieces, the at least one extra-annular portion including an over-annular portion to extend collar-like over the annulus of the natural valve site at the inflow side of the blood flow lumen. - View Dependent Claims (18, 19, 20, 21)
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Specification