BIOSENSOR

• US 20130256131A1
• Filed: 04/03/2013
• Published: 10/03/2013
• Est. Priority Date: 04/03/2012
• Status: Active Grant

• Current Assignee: Joinsoon Medical Technology Co., Ltd.
• Original Assignee: Joinsoon Medical Technology Co., Ltd.
• Inventors: Lee, Jen Fang
• Granted Patent: US 9,759,677 B2
• Time in Patent Office: Days
• US Class Current: 204/403.01
• CPC Class Codes: G01N 27/327 Biochemical electrodes , e.g. electrical or mechanical details for in vitro measurements

Abstract

The present invention disclosed a biosensor apparatus comprising a substrate on which a reaction region is defined, a fluid channel defining a path to the reaction region, and a venting means communicably coupled with the fluid channel and opening exterior of the biosensor apparatus at a perimeter side of the biosensor apparatus. The present invention allows air to exit the fluid channel through perimeter sides of the biosensor apparatus without adding significant manufacturing complexity.

Claims

1. A biosensor apparatus comprising:

a substrate on which a reaction region is defined;

a fluid channel defining a path to the reaction region; and

a venting means communicably coupled with the fluid channel and opening exterior of the biosensor apparatus at a perimeter side of the biosensor apparatus.

2. The apparatus of claim 1, wherein the venting means comprises at least one part of a linear passageway that is substantially perpendicular to the path of the fluid channel.

3. The apparatus of claim 1, further comprising a spacer layer disposed on the substrate to define the fluid channel, and a cover layer disposed on the spacer layer.

4. The apparatus of claim 3, wherein the cover layer comprises an optically transparent material and wherein a bottom surface of the cover layer adjacent the fluid channel is hydrophilic.

5. The apparatus of claim 3, wherein the venting means comprises a passageway disposed on a bottom surface of the cover layer for discharging the air through one or more of lateral sides and back side of the cover layer.

6. The apparatus of claim 3, wherein the venting means comprises a passageway disposed on an upper surface of the substrate for discharging the air through one or more of lateral sides of the substrate and a back side of the spacer layer opposing an opening of the fluid channel.

7. The apparatus of claim 3, wherein the venting means comprises a passageway disposed on the spacer layer and communicably coupled to an end portion of the fluid channel, the passageway capable of discharging the air through one or more sides of the spacer layer.

8. The apparatus of claim 1, further comprising a dielectric layer disposed on the substrate, the dielectric layer comprising a reaction chamber that defines the reaction region.

9. The apparatus of claim 8, wherein the venting means comprises a passageway disposed on a rear portion of the dielectric layer for discharging the air through one or more of lateral sides and a back side of the dielectric layer.

10. The apparatus of claim 8, wherein the dielectric layer comprises a stopping chamber communicably coupled between an end portion of the fluid channel and the venting means, wherein the stopping chamber comprises a cross sectional area substantially greater than that of the fluid channel.

11. The apparatus of claim 3, wherein the spacer layer further defines a stopping chamber at an end portion of the fluid channel, the stopping chamber having a cross sectional area substantially greater than that of the fluid channel.

12. The apparatus of claim 1, further comprising a stopping chamber communicably coupled between the fluid channel and the venting means, wherein the stopping chamber comprises a cross sectional area substantially greater than that of the fluid channel.

13. The apparatus of claim 1, wherein a top surface, a bottom surface, and said perimeter side define a geometrical dimension of the biosensor apparatus.

14. A biosensor apparatus comprising:

a substrate on which a reaction region is defined;

a fluid channel for introducing a fluid sample to the reaction region;

a venting channel communicably coupled with the fluid channel; and

a sample reservoir communicably coupled between the fluid channel and the venting channel.

15. The apparatus of claim 14, wherein the sample reservoir comprises a cross sectional area substantially greater than that of the fluidic channel.

16. The apparatus of claim 14, further comprising a spacer layer disposed on the substrate to define the fluid channel.

17. The apparatus of claim 16, further comprising a cover layer disposed on the spacer layer, wherein the venting channel is disposed on a bottom surface of the cover layer for discharging the air through a perimeter side of the cover layer.

18. The apparatus of claim 16, wherein the venting channel is disposed on a rear portion of the spacer layer for discharging the air through a perimeter side of the space layer.

19. The apparatus of claim 14, wherein the venting channel is disposed on an upper surface of the substrate for discharging the air through a perimeter side of the substrate.

20. The apparatus of claim 16, further comprising a dielectric layer disposed between the spacer layer and the substrate, the dielectric layer comprising a reaction chamber that defines the reaction region, and a stopping chamber that defines the sample reservoir.

21. The apparatus of claim 20, wherein the stopping chamber comprises a cross sectional area substantially greater than that of the fluid channel.