CHIP FOR ANALYSIS OF SOLUTION OF INTEREST

• US 20130266491A1
• Filed: 12/16/2011
• Published: 10/10/2013
• Est. Priority Date: 12/17/2010
• Status: Abandoned Application

• Current Assignee: Horiba Limited
• Original Assignee: Horiba Limited
• Inventors: Murata, Tomoyuki
• Application Number:
  US13/995,114
• Publication Number:
  US 20130266491A1
• Time in Patent Office: Days
• US Class Current: 422/547
• CPC Class Codes: B01L 2200/0684 Venting, avoiding backpressure, avoid gas bubbles
• CPC Class Codes: B01L 2200/141 Preventing contamination, tampering
• CPC Class Codes: B01L 2300/0681 Filter
• CPC Class Codes: B01L 2300/0887 Laminated structure
• CPC Class Codes: B01L 2300/161 Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
• CPC Class Codes: B01L 2400/0406 capillary forces
• CPC Class Codes: B01L 3/5027 by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip B01L3/5023 takes precedence; micromixers B01F33/30; microreactors for synthesis B01J19/0093; microcapillary devices in general B81B1/00
• CPC Class Codes: B01L 3/502707 characterised by the manufacture of the container or its components by shaping or joining plastic parts B29C59/00, B29C65/00; by laminating B32B37/00; manufacture of microstructural devices in general B81C
• CPC Class Codes: B01L 3/508 rigid containers not provided for above
• CPC Class Codes: G01N 2035/00158 Elements containing microarrays, i.e. "biochip"
• CPC Class Codes: G01N 27/3271 Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood amperometry per se G01N27/49; aspects concerning the enzyme reagent C12Q1/001

Abstract

The present invention provides a chip which can be used for preventing the contamination in the inside of a measurement device, and comprises: a contact hole that is in contact with a solution of interest and that is formed on an outer surface of the chip for the purpose of introducing blood that makes contact with the contact hole into the inside of the chip; a first hydrophobic region that is substantially in contact with at least a part of an opening edge of the contact hole and that is formed on the outer surface of the chip from a contact hole toward the chip insertion side; and a first hydrophilic region that is located adjacent to the first hydrophobic region and that is formed on the outer surface of the chip from the first hydrophobic region toward the chip insertion side.

Claims

1. A chip for analysis of solution of interest that is inserted into an inside of a measurement device and that is for analyzing a solution of interest, wherein comprising

a contact hole that is in contact with the solution of interest and that is formed on an outer surface of the chip for the purpose of introducing the solution of interest that makes contact with the contact hole into the inside of the chip,

a first hydrophobic region that is substantially in contact with an opening edge of the contact hole and that is formed from the contact hole to a chip insertion side on the outer surface of the chip, and

a first hydrophilic region that is located adjacent to the first hydrophobic region and that is formed from the first hydrophobic region to the chip insertion side on the outer surface of the chip.

2. The chip for analysis of solution of interest described in claim 1, and further comprising

a second hydrophobic region that is located adjacent to the first hydrophilic region and that is formed from the first hydrophilic region to the chip insertion side on the outer surface of the chip.

3. The chip for analysis of solution of interest described in claim 1, wherein comprising

a grip part that is arranged on an opposite side to the chip insertion side and that is gripped in case that the chip is inserted in the inside of the measurement device,

a second hydrophilic region that is located adjacent to the first hydrophobic region and that is formed from the first hydrophobic region to a grip part side on the outer surface of the chip, and

a third hydrophobic region that is located adjacent to the second hydrophilic region and that is formed from the second hydrophilic region to the grip part side on the outer surface of the chip.

4. The chip for analysis of solution of interest described in claim 2, wherein

a boundary between the first hydrophilic region and the second hydrophobic region is located outside of the measurement device in a state that the chip is inserted into the measurement device.

5. The chip for analysis of solution of interest described in claim 1, wherein

the contact hole opens from a side surface of the chip to a back surface of the chip and

the first hydrophobic region and the first hydrophilic region are formed on the back surface of the chip.