SYSTEM AND METHOD FOR THE SIMULTANEOUS, NON-INVASIVE ESTIMATION OF BLOOD GLUCOSE, GLUCOCORTICOID LEVEL AND BLOOD PRESSURE
First Claim
1. System for the simultaneous and non-invasive estimation of glucose in blood, glucocorticoid levels and blood pressure, based on a person'"'"'s distal heartbeat waveform, acquired from a sensor, which provides a digitalized signal, comprising:
- an activity detection module for said digitalized signal, which selects a segment of consecutive samples from said digitalized signal, with a fixed duration and which are referred to as Swindow(t) and, based on the same, generates a sequence of sub-windows or frames referred to as Sframe(t, n) which are shorter in duration than those of Swindow(t), wherein the index t indicates the sample number within a frame and n represents the frame number;
a signal processing module which receives the two signals Swindow(t) and Sframe(t, n) containing the waveform of the distal heartbeat in a fixed duration module, and which provides an XF vector as output, which in turn contains the parameters of a physiological model; and
an automatic learning based module to which said XF vector is fed alongside information on the characteristics of the person and which provides an estimation of blood glucose levels (BGL), systolic pressure levels (SPL), diastolic pressure levels (DPL) and glucocorticoid levels (GCL) as output.
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Abstract
System and method for the simultaneous and non-invasive estimation of blood glucose, glucocorticoid and pressure levels. It comprises an activity module detector for a digitalized signal acquired by a sensor, representing the distal heartbeat of a person, selecting a segment of consecutive signal samples of fixed duration Swindow(t) and using the same to generate sub-windows Sframe(t, n) of shorter duration; a signal processing module which receives the two signals Swindow(t) and Sframe(t, n) and which delivers a vector XF at its output with the parameters of a physiological model and module based on automatic learning, which receives the XF vector and information on a person'"'"'s characteristics and provides an estimation of blood glucose levels (BGL), systolic pressure levels (SPL), diastolic pressure levels (DPL) and glucocorticoid levels (GCL) at its output.
52 Citations
17 Claims
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1. System for the simultaneous and non-invasive estimation of glucose in blood, glucocorticoid levels and blood pressure, based on a person'"'"'s distal heartbeat waveform, acquired from a sensor, which provides a digitalized signal, comprising:
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an activity detection module for said digitalized signal, which selects a segment of consecutive samples from said digitalized signal, with a fixed duration and which are referred to as Swindow(t) and, based on the same, generates a sequence of sub-windows or frames referred to as Sframe(t, n) which are shorter in duration than those of Swindow(t), wherein the index t indicates the sample number within a frame and n represents the frame number; a signal processing module which receives the two signals Swindow(t) and Sframe(t, n) containing the waveform of the distal heartbeat in a fixed duration module, and which provides an XF vector as output, which in turn contains the parameters of a physiological model; and an automatic learning based module to which said XF vector is fed alongside information on the characteristics of the person and which provides an estimation of blood glucose levels (BGL), systolic pressure levels (SPL), diastolic pressure levels (DPL) and glucocorticoid levels (GCL) as output. - View Dependent Claims (2, 3, 4, 5, 6)
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7. Method for the simultaneous and non-invasive estimation of glucose in blood, glucocorticoid levels and blood pressure, based on a person'"'"'s distal heartbeat waveform, acquired from a sensor, which provides a digitalized signal, comprising:
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detecting the activity of said digitalized signal by selecting a segment of consecutive samples of said digitalized signal, of fixed duration and referred to as Swindow(t) and using said segment to generate a sequence of sub-windows or frames referred to as Sframe(t, n) and of lesser duration than those of Swindow(t), wherein the index t indicates the sample number within a frame and n represents the frame number making it possible to eliminate those signal segments which are not useful, comprising the initial transition, false clicks, signal losses, noise and saturation; processing the two signals Swindow(t) and Sframe(t, n), which contain the distal heartbeat waveform in a fixed duration segment and based on the same, generating an XF vector, which contains the parameters of a physiological model; and feeding said XF vector and information on a person'"'"'s characteristics into a module based on automatic learning and which provides an estimate of blood glucose levels (BGL), systolic pressure levels (SPL), diastolic pressure levels (DPL) and glucocorticoid levels (GCL) as output. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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Specification