CELL AND TISSUE COLLECTION METHOD AND DEVICE
First Claim
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1. A device for contacting an epithelial tissue to obtain a biopsy tissue sample comprising:
- (a) a head with a proximal end, a distal end, a volume, and a cavity, where the proximal end of the head is attached to a cannula;
(b) a balloon adapted to expand from the cavity; and
(c) an abrasive material associated with a surface of the balloon, where the abrasive material on the balloon is adapted to contact the epithelial tissue to obtain the biopsy tissue sample.
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Abstract
In an embodiment of the invention, a frictional tissue sampling device with an expandable balloon and associated abrasive material can be used to obtain tissue biopsy samples. A frictional tissue sampling device with expandable abrasive material can be used to obtain an epithelial tissue biopsy sample from lesions. The device can be otherwise used to sample specific locations. In various embodiments, the head of the device can be passes through a catheter into a body canal to sample epithelial tissue.
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Citations
20 Claims
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1. A device for contacting an epithelial tissue to obtain a biopsy tissue sample comprising:
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(a) a head with a proximal end, a distal end, a volume, and a cavity, where the proximal end of the head is attached to a cannula; (b) a balloon adapted to expand from the cavity; and (c) an abrasive material associated with a surface of the balloon, where the abrasive material on the balloon is adapted to contact the epithelial tissue to obtain the biopsy tissue sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A method of obtaining a biopsy sample from epithelial tissue of a body canal comprising:
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(a) inserting a catheter into the body canal; (b) inserting a cannula with a head including a balloon with an abrasive material associated with the balloon into the catheter in the body canal; (c) inflating the balloon inside the body canal, where the abrasive material contacts the epithelial tissue of the body canal; (d) rotating the head in a first direction to frictionally abrade the epithelial tissue with the abrasive material; (e) deflating the balloon; and (f) removing the cannula with the head including the balloon and the abrasive material from the catheter.
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20. A device for obtaining a biopsy tissue sample comprising:
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(a) a head with a proximal end, a distal end, and a diameter, where the proximal end of the head is attached to a cannula; (b) a balloon associated with the head; (c) an abrasive material associated with a surface of the balloon, where the balloon can be inflated; and (d) abrasive material associated with the head.
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Specification