Transcatheter Stent-Valves and Methods, Systems and Devices for Addressing Para-Valve Leakage

• US 20130274873A1
• Filed: 03/15/2013
• Published: 10/17/2013
• Est. Priority Date: 03/22/2012
• Status: Abandoned Application

• Current Assignee: Symetis SA (Boston Scientific Corporation)
• Original Assignee: Symetis SA (Boston Scientific Corporation)
• Inventors: Delaloye, Stephane, Essinger, Jacques, Hefti, Jean-Luc, Biadillah, Youssef, Mantanus, Luc, Lombardi, Fabien
• Application Number:
  US13/839,357
• Publication Number:
  US 20130274873A1
• Time in Patent Office: Days
• US Class Current: 623/2.18
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2469 with resilient valve members, e.g. conical spiral
• CPC Class Codes: A61F 2210/0061 swellable
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2250/0003 having an inflatable pocket filled with fluid, e.g. liquid or gas
• CPC Class Codes: A61F 2250/0069 Sealing means

Abstract

Some embodiments of the present disclosure provide a stent-valve for transcatheter implantation to replace a cardiac valve. In some embodiments, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation. In some embodiments, the stent-valve comprises a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprising material that swells in response to contact with blood or components thereof.

Claims

1. A stent-valve for transcatheter implantation to replace a cardiac valve, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation, the stent-valve comprising a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue, the paravalve seal comprising material that swells in response to contact with blood.

2. The stent-valve of claim 1, wherein at least one of the skirts comprises the swellable material.

3. The stent-valve of claim 1, wherein the stent comprises at least one of:

a lower tubular portion;

an upper crown portion;

a plurality of upstanding commissural supports;

a plurality of stabilization arches.

4. The stent-valve of claim 3, wherein the stent comprises the lower tubular portion, the upper crown portion, the plurality of upstanding commissural supports, and the plurality of stabilization arches.

5. The stent-valve of claim 4, wherein the lower tubular portion communicates with the upper crown and the commissural supports, wherein the commissural supports upstand relative to the upper crown portion, and wherein the stabilization arches communicate with the commissural supports.

6. The stent-valve of claim 4, wherein the swellable material is positioned between and spaced from respective extremities of both a free edge of the upper crown, and a free edge of the lower tubular portion.

7. The stent-valve of claim 4, wherein the lower tubular portion is configured for deployment after at least partial deployment of the upper crown portion, the commissural supports and the stabilization arches.

8. The stent-valve of claim 1, wherein the outer skirt comprises fabric comprising fibers of the swellable material.

9. The stent-valve of claim 1, wherein the swellable material is captive within a containing chamber, the containing chamber carried by the outer skirt.

10. A stent-valve for transcatheter implantation to replace a cardiac valve, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation, the stent-valve comprising a stent, a plurality of leaflets for defining a prosthetic valve, and a paravalve seal for sealing against surrounding tissue, the paravalve seal comprising material that swells in response to contact with blood, the paravalve seal being positioned towards one extremity of the stent, and spaced from said one extremity.

11. The stent-valve of claim 10, wherein said one extremity of the stent comprises a zig-zag edge, the zig-zag edge including first apexes alternating with second apexes, wherein the paravalve seal is positioned such that it does not extend in the region between the apexes.