SYSTEMS AND METHODS FOR TRIGGERING AND CYCLING A VENTILATOR BASED ON RECONSTRUCTED PATIENT EFFORT SIGNAL

• US 20130276788A1
• Filed: 06/24/2013
• Published: 10/24/2013
• Est. Priority Date: 06/06/2008
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Masic, Milenko
• Granted Patent: US 9,114,220 B2
• Time in Patent Office: Days
• US Class Current: 128/204.23
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61M 16/0003 Accessories therefor, e.g. sensors, vibrators, negative pressure
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/0057 Pumps therefor
• CPC Class Codes: A61M 16/026 specially adapted for predicting, e.g. for determining an information representative of a flow limitation during a ventilation cycle by using a root square technique or a regression analysis
• CPC Class Codes: A61M 16/12 by mixing different gases
• CPC Class Codes: A61M 2016/0015 inhalation detectors
• CPC Class Codes: A61M 2016/0018 electrical
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2016/0036 in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2016/0039 in the inspiratory circuit
• CPC Class Codes: A61M 2016/0042 in the expiratory circuit
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: G01F 1/00 Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow measuring a proportion of the volume flow G01F5/00
• CPC Class Codes: G01F 1/34 by measuring pressure or differential pressure

Abstract

Various embodiments of the present disclosure provide systems, methods and devices for respiratory support. As one example, a method for respiratory support is described that includes providing a measured pressure, and calculating a net flow based on at least one measured inlet flow and measured outlet flow. A relationship between a first value related to the measured pressure, a second value related to the measured net flow and a third value related to patient effort is used to provide a prediction of patient effort. An interim value is updated based at least in part on the prediction of the patient effort, and used to help compute a patient effort. A ventilation cycle is initiated using the computed patient effort.

Claims

1-22. -22. (canceled)

23. A method for respiratory support, the method comprising:

providing a measured pressure;

calculating a net flow based on at least one measured inlet flow and at least one measured outlet flow;

using a relationship between a first value related to the measured pressure, a second value related to the measured net flow and a third value related to patient effort to provide a prediction of patient effort;

updating an interim value based at least in part on the prediction of patient effort, wherein the interim value is one of a covariance matrix and a parameter vector; and

calculating a computed patient effort based at least in part on the interim value.

24. The method of claim 23, wherein the computed patient effort is a filtered patient effort signal.

25. The method of claim 23, wherein the computed patient effort is a linear function of a derivative of actual patient effort.

26. The method of claim 23, further comprising triggering a ventilation cycle based at least in part on the computed patient effort.

27. The method of claim 26, further comprising:

determining a negative zero crossing of the computed patient effort, and

initiating the ventilation cycle based at least in part on the negative zero crossing of the computed patient effort.

28. The method of claim 26, further comprising:

determining a positive zero crossing of the computed patient effort, and

terminating the ventilation cycle based at least in part on the positive zero crossing of the computed patient effort.

29. The method of claim 26, further comprising:

determining an onset condition related to the computed patient effort, and

initiating the ventilation cycle based at least in part on the onset condition.

30. The method of claim 29, wherein the computed patient effort is a function of a derivative of actual patient effort, and wherein determining the onset condition includes determining whether the computed patient effort passes through a threshold value with a negative slope.

31. The method of claim 30, wherein determining the onset condition occurs outside of an inspiration cycle.

32. The method of claim 30, wherein the threshold value is zero.

33. The method of claim 26, further comprising:

determining an end condition, and

terminating the ventilation cycle based at least in part on the end condition.

34. The method of claim 33, wherein the computed patient effort is a function of a derivative of actual patient effort, and wherein determining the end condition includes determining whether the computed patient effort passes through a threshold value with a positive slope.

35. The method of claim 34, wherein determining the end condition occurs during an inspiration cycle.

36. The method of claim 34, wherein the threshold value is zero.

37. A ventilation system, the ventilation system comprising:

a processor communicably coupled to a computer readable medium, wherein the computer readable medium includes instructions executable by the processor to;

receive a pressure;

receive at least one of an inlet flow and an outlet flow;

use a relationship between a first value related to the pressure, a second value related to the received flow, and a third value related to patient effort to calculate a prediction of patient effort;

update an interim value based at least in part on the prediction of patient effort, wherein the interim value is one of a covariance matrix and a parameter vector; and

calculate a computed patient effort based at least in part on the interim value.

38. The system of claim 37, further comprising:

trigger a ventilation cycle based at least in part on the computed patient effort.

39. The system of claim 38, further comprising:

determine an end condition, and

terminate the ventilation cycle based at least in part on the end condition.

40. The system of claim 39, wherein the computed patient effort is a function of a derivative of actual patient effort, and wherein determining the end condition includes determining whether the computed patient effort passes through a threshold value with a positive slope.

41. The system of claim 38, further comprising:

determine an onset condition, and

trigger the ventilation cycle based at least in part on the onset condition.

42. The system of claim 41, wherein the computed patient effort is a function of a derivative of actual patient effort, and wherein determining the onset condition includes determining whether the computed patient effort passes through a threshold value with a negative slope.

43. A patient ventilator, the ventilator comprising:

a gas inlet;

a gas outlet;

a tube coupling the gas inlet and the gas outlet;

a pressure sensor, wherein the pressure sensor is operable to provide a measured pressure value indicating a pressure in the tube;

a first flow sensor, wherein the first flow sensor is operable to provide an inlet flow value indicating a flow associated with the gas inlet;

a second flow sensor, wherein the second flow sensor is operable to provide an outlet flow value indicating a flow associated with the gas outlet; and

a processor communicably coupled to a computer readable medium, wherein the computer readable medium includes instructions executable by the processor to;

receive the measured pressure value;

receive the inlet flow value;

receive the outlet flow value;

calculate a net flow based at least in part on the inlet flow value and the outlet flow value;

use a relationship between a first value related to the measured pressure, a second value related to the net flow and a third value related to patient effort to provide a prediction of patient effort;

update an interim value based at least in part on the prediction of patient effort, wherein the interim value is one of a covariance matrix and a parameter vector; and

calculate a computed patient effort based at least in part on the interim value.

44. The patient ventilator as in claim 43, further comprising:

trigger a ventilation cycle based at least in part on the computed patient effort.