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3,5,3'-Triiodothyronine Sulfate As Thyromimetic Agent And Pharmaceutical Formulations Thereof

  • US 20130281536A1
  • Filed: 06/13/2013
  • Published: 10/24/2013
  • Est. Priority Date: 11/13/2002
  • Status: Active Grant
First Claim
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1. A solid oral dosage composition comprising T3S as the active principle, in a quantity ranging from 1 to 1000 μ

  • g further comprising;

    a) a diluent consisting of;

    an alkaline inorganic salt and microcrystalline cellulose;

    b) a disintegrant selected in the group consisting of;

    corn starch, croscarmellose or salts thereof, crospovidone or salts thereof, polymethacrylates and maltodextrin or salts thereof;

    c) a glidant selected in the group consisting of;

    glycerol dibehenate, tri-basic calcium phosphate, starch derivatives, talc, magnesium stearate and zinc stearate; and

    d) a lubricant selected from the group consisting of;

    silicates, including hydrate silicon dioxide, hydrate colloidal silica;

    magnesium stearate;

    zinc stearate; and

    talc.

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