Closed Loop Blood Glucose Control Algorithm Analysis

• US 20130282301A1
• Filed: 06/17/2013
• Published: 10/24/2013
• Est. Priority Date: 04/28/2009
• Status: Abandoned Application

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Rush, Benjamin Mark
• Application Number:
  US13/920,068
• Publication Number:
  US 20130282301A1
• Time in Patent Office: Days
• US Class Current: 702/21
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: G01N 33/49 Blood chemical methods for determining blood cell populations G01N33/5094; chemical analysis of blood groups or blood types G01N33/80
• CPC Class Codes: G16B 99/00 Subject matter not provided for in other groups of this subclass
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

Methods and devices to generate a tool for testing, simulating and/or modifying a closed loop control algorithm are provided. Embodiments include receiving glucose data for a predetermined time period, determining a variation in the glucose level based on the received glucose data, filtering a received glucose data based on the determined variation, substituting a negative change in the glucose data value with a predetermined value to generate a sequence of modified glucose values, and integrating the sequence of modified glucose values to determine an uncontrolled blood glucose excursion condition.

Claims

1. A method, comprising:

receiving glucose data for a predetermined time period;

determining a variation in the glucose level based on the received glucose data;

filtering the received glucose data based on the determined variation;

substituting a negative change in the glucose data value with a predetermined value to generate a sequence of modified glucose values; and

integrating the sequence of modified glucose values to determine an uncontrolled blood glucose excursion condition.

2. The method of claim 1 wherein the predetermined value includes an average value.

3. The method of claim 2 wherein the average value includes an average of ten prior values.

4. The method of claim 2 wherein the average value includes a weighted average value.

5. The method of claim 4 wherein the weighed average value includes an equally weighted average value.

6. The method of claim 4 wherein the weighed average value includes an unequally weighted average value.

7. The method of claim 2 wherein the average value includes an unweighted average value.

8. The method of claim 1 wherein filtering based on the predetermined variation includes filtering out glucose values associated with a negative change.

9. The method of claim 8 wherein the negative change is determined based on an immediate prior glucose value.

10. An apparatus, comprising:

a user interface;

one or more processors operatively coupled to the data user interface; and

a memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to receive glucose data for a predetermined time period, determine a variation in the glucose level based on the received glucose data, filter the received glucose data based on the determined variation, substitute a negative change in the glucose data value with a predetermined value to generate a sequence of modified glucose values, and integrating the sequence of modified glucose values to determine an uncontrolled blood glucose excursion condition.

11. The apparatus of claim 10 wherein the predetermined value includes an average value.

12. The apparatus of claim 11 wherein the average value includes an average of ten prior values.

13. The apparatus of claim 10 wherein the average value includes a weighted average value.

14. The apparatus of claim 13 wherein the weighed average value includes an equally weighted average value.

15. The apparatus of claim 13 wherein the weighed average value includes an unequally weighted average value.

16. The apparatus of claim 10 wherein the average value includes an unweighted average value.

17. The apparatus of claim 10 wherein the memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to filter out glucose values associated with a negative change.

18. The apparatus of claim 17 wherein the negative change is determined based on an immediate prior glucose value.

19. One or more storage devices having processor readable code embodied thereon, said processor readable code for programming one or more processors to perform a control test algorithm, comprising:

receiving glucose data for a predetermined time period;

determining a variation in the glucose level based on the received glucose data;

filtering the received glucose data based on the determined variation;

substituting a negative change in the glucose data value with a predetermined value to generate a sequence of modified glucose values; and

integrating the sequence of modified glucose values to determine an uncontrolled blood glucose excursion condition.