BIOLOGICAL TISSUE FOR SURGICAL IMPLANTATION
First Claim
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1. A method of manufacturing a bioprosthetic heart valve comprising:
- providing a biological tissue and a stent;
contacting the biological tissue with a treatment solution comprising a polyhydric alcohol and an alcohol that is different from the polyhydric alcohol;
mounting the biological tissue to the stent to produce a bioprosthetic heart valve;
wherein the biological tissue remains pliable following the contacting; and
wherein the contacting is performed either before or after the mounting.
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Abstract
A method of treating a biological tissue that enables dry storage of said tissue is disclosed. In one embodiment, the method comprises contacting the biological tissue with a non-aqueous treatment solution comprising a polyhydric alcohol and a C1-C3 alcohol and removing a portion of the treatment solution from the solution-treated biological tissue. Also disclosed is biological tissue prepared using the above process and prosthetic devices made with such tissue.
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Citations
14 Claims
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1. A method of manufacturing a bioprosthetic heart valve comprising:
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providing a biological tissue and a stent; contacting the biological tissue with a treatment solution comprising a polyhydric alcohol and an alcohol that is different from the polyhydric alcohol; mounting the biological tissue to the stent to produce a bioprosthetic heart valve; wherein the biological tissue remains pliable following the contacting; and wherein the contacting is performed either before or after the mounting. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification