SIGNATURES OF ELECTROENCEPHALOGRAPHIC OSCILLATIONS
First Claim
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1. A method comprising:
- determining the presence or absence of a signature in electroencephalographic oscillations recorded from a subject during onset of an exploratory activity engaged in by the subject, wherein presence of the signature in the electroencephalographic oscillations is indicative of absence of a cognitive disorder in the subject, and wherein absence of the signature in the electroencephalographic oscillations is indicative of presence of the cognitive disorder in the subject.
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Abstract
The present invention provides, in some aspects, methods for identifying and evaluating signatures in electroencephalographic oscillations that occur during onset of an exploratory activity in a subject.
17 Citations
35 Claims
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1. A method comprising:
determining the presence or absence of a signature in electroencephalographic oscillations recorded from a subject during onset of an exploratory activity engaged in by the subject, wherein presence of the signature in the electroencephalographic oscillations is indicative of absence of a cognitive disorder in the subject, and wherein absence of the signature in the electroencephalographic oscillations is indicative of presence of the cognitive disorder in the subject. - View Dependent Claims (4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19, 20, 34)
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2. A method comprising:
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administering a test agent to subject who is identified as having a cognitive disorder; and determining the presence or absence of a signature in electroencephalographic oscillations recorded from the subject during onset of an exploratory activity engaged in by the subject after having been administered the test agent, wherein presence of the signature in the electroencephalographic oscillations is indicative of effectiveness of the test agent in treating the cognitive disorder, and wherein absence of the signature in the electroencephalographic oscillations is indicative of a lack of effectiveness of the test agent in treating the cognitive disorder.
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3. A method of diagnosing, or aiding in diagnosing, a subject as having a cognitive disorder comprising:
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identifying a subject suspected of having a cognitive disorder or at risk of having the cognitive disorder; and determining the presence or absence of a signature in electroencephalographic oscillations recorded from the subject during onset of an exploratory activity engaged in by the subject, wherein presence of the signature in the electroencephalographic oscillations is indicative of absence of a cognitive disorder in the subject, and wherein absence of the signature in the electroencephalographic oscillations is indicative of presence of the cognitive disorder in the subject.
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17. (canceled)
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21-33. -33. (canceled)
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35-52. -52. (canceled)
Specification